This is a competitive renewal of the training program in Neonatal and Developmental Diseases within the existing Neonatology Program at the David Geffen School of Medicine at UCLA. This is a three to four year training program geared towards training postresident neonatology fellows (M.D. and M.D., Ph.D.) with the idea of developing independent and productive physician-scientists with training of postdoctoral Ph.D. fellows in the area of Neonatal and Developmental Diseases. This program strives to attract individuals with a commitment towards academic medicine, provides a scientifically rich environment where M.D. and Ph.D. postresident and postdoctoral trainees are afforded the opportunity of training side-by-side in established laboratories/research programs with expertise in developmental biology, genetics, molecular biology, cell biology, and translational investigation. Program faculty has been chosen from diverse fields and from departments at the School of Medicine, with a nationally reputable research program and a proven track record in training scientists and clinicians. The program is structured to include clinical neonatology training (as per the requirements spelled out by the American Board of Pediatrics) the bulk of which occurs during the first year;the second and third years are devoted to training in laboratory-based or translational research for the postresidency fellows. Following this initial training period, and after rigorous evaluation, the postresidency fellows are allowed to progress into the postdoctoral portion of their fellowship that consists of one additional year (year four) following which they are expected to obtain independent funding for their research programs. This training program requests support from NICHD for only years two, three and four of training. In addition, postdoctoral Ph.D. fellows are afforded a three year training period, of which this program requests funds for only the first year, with the expectation that they obtain independent postdoctoral fellowship support from independent applications for support. Given the available faculty members, the facilities, the curricular and administrative structure, the formal selection and evaluation processes, and the expectations both at recruitment and throughout the training period, this training program is expected to continue producing independent investigators in the field of Neonatal and Developmental Diseases.

National Institute of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
Pediatrics Subcommittee (CHHD)
Program Officer
Raju, Tonse N
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of California Los Angeles
Schools of Medicine
Los Angeles
United States
Zip Code
Calkins, Kara L; Sanchez, Lauren A; Tseng, Chi-Hong et al. (2016) Effect of High-Dose Cysteine Supplementation on Erythrocyte Glutathione: A Double-Blinded, Randomized Placebo-Controlled Pilot Study in Critically Ill Neonates. JPEN J Parenter Enteral Nutr 40:226-34
Gibson, Leena Caroline; Shin, Bo-Chul; Dai, Yun et al. (2015) Early leptin intervention reverses perturbed energy balance regulating hypothalamic neuropeptides in the pre- and postnatal calorie-restricted female rat offspring. J Neurosci Res 93:902-12
Farzin, Azadeh; Boyer, Pamela; Ank, Bonnie et al. (2013) Amniotic fluid exhibits an innate inhibitory activity against HIV type 1 replication in vitro. AIDS Res Hum Retroviruses 29:77-83
Abbasi, Afshan; Thamotharan, Manikkavasagar; Shin, Bo-Chul et al. (2012) Myocardial macronutrient transporter adaptations in the adult pregestational female intrauterine and postnatal growth-restricted offspring. Am J Physiol Endocrinol Metab 302:E1352-62
Fung, Camille; Evans, Edward; Shin, Don et al. (2010) Hypoxic-ischemic brain injury exacerbates neuronal apoptosis and precipitates spontaneous seizures in glucose transporter isoform 3 heterozygous null mice. J Neurosci Res 88:3386-98
Zhao, Y; Fung, C; Shin, D et al. (2010) Neuronal glucose transporter isoform 3 deficient mice demonstrate features of autism spectrum disorders. Mol Psychiatry 15:286-99
Soliman, Antoine; Michelsen, Kathrin S; Karahashi, Hisae et al. (2010) Platelet-activating factor induces TLR4 expression in intestinal epithelial cells: implication for the pathogenesis of necrotizing enterocolitis. PLoS One 5:e15044
Evans, E; Koh, S; Lerner, Jt et al. (2010) Accuracy of amplitude integrated EEG in a neonatal cohort. Arch Dis Child Fetal Neonatal Ed 95:F169-73
Kurlawalla-Martinez, Christine; Stiles, Bangyan; Wang, Ying et al. (2005) Insulin hypersensitivity and resistance to streptozotocin-induced diabetes in mice lacking PTEN in adipose tissue. Mol Cell Biol 25:2498-510
Widney, Daniel P; Hu, Yan; Foreman-Wykert, Amy K et al. (2005) CXCR3 and its ligands participate in the host response to Bordetella bronchiseptica infection of the mouse respiratory tract but are not required for clearance of bacteria from the lung. Infect Immun 73:485-93

Showing the most recent 10 out of 16 publications