The investigators request continued support for the Multidisciplinary Training Program in Neuroscience at Oregon Health &Science University (OHSU). This program, which is about to enter its tenth year, offers broad-based, early stage training for students in OHSU's two Ph.D.-granting neuroscience programs, the Neuroscience Graduate Program and the Behavioral Neuroscience Graduate Program;together these programs enroll about 90 students. The program of training proposed is based on a strong core curriculum that provides a common knowledge base for subsequent training in the classroom and at the bench, together with extensive and varied opportunities for research, beginning as soon as students enter the Program. The training faculty of 65 scientists offers research opportunities that range from fundamental studies of nerve cell function to translational research programs that target nervous system disorders. Through workshops and individual instruction, the Program also provides instruction in scientific communication skills and career development. The spirit of collegiality that has developed at OHSU combined with the diversity of its many research institutes and the close proximity of basic and clinical research facilities provide a unique opportunity for predoctoral students to form cross-disciplinary collaborations during their training, and to gain an appreciation for the growing importance of neuroscience research in the treatment of neural disease.
This Program will train Ph.D. students in neuroscience, providing them with the knowledge base and technical skills to enable them to conduct original research on the biological bases of nervous system disease.
|McPherson, Kylie B; Leff, Emily R; Li, Ming-Hua et al. (2018) Regulators of G-Protein Signaling (RGS) Proteins Promote Receptor Coupling to G-Protein-Coupled Inwardly Rectifying Potassium (GIRK) Channels. J Neurosci 38:8737-8744|
|Villasana, Laura E; Weber, Sydney; Akinyeke, Tunde et al. (2016) Genotype differences in anxiety and fear learning and memory of WT and ApoE4 mice associated with enhanced generation of hippocampal reactive oxygen species. J Neurochem 138:896-908|
|Dufour, Brett D; McBride, Jodi L (2016) Intravascular AAV9 Administration for Delivering RNA Silencing Constructs to the CNS and Periphery. Methods Mol Biol 1364:261-75|
|Dufour, Brett D; Smith, Catherine A; Clark, Randall L et al. (2014) Intrajugular vein delivery of AAV9-RNAi prevents neuropathological changes and weight loss in Huntington's disease mice. Mol Ther 22:797-810|
|Keith, Dove J; Wolfrum, Katherine; Eshleman, Amy J et al. (2012) Melittin initiates dopamine transporter internalization and recycling in transfected HEK-293 cells. Eur J Pharmacol 690:13-21|
|Gantz, Stephanie C; Ford, Christopher P; Neve, Kim A et al. (2011) Loss of Mecp2 in substantia nigra dopamine neurons compromises the nigrostriatal pathway. J Neurosci 31:12629-37|
|Roalf, David R; Pruis, Trisha A; Stevens, Alexander A et al. (2011) More is less: emotion induced prefrontal cortex activity habituates in aging. Neurobiol Aging 32:1634-50|
|Richard, Christian D; Tolle, Virginie; Low, Malcolm J (2011) Meal pattern analysis in neural-specific proopiomelanocortin-deficient mice. Eur J Pharmacol 660:131-8|
|Benice, Ted S; Raber, Jacob (2010) Castration and training in a spatial task alter the number of immature neurons in the hippocampus of male mice. Brain Res 1329:21-9|
|Villasana, Laura; Rosenberg, Jenna; Raber, Jacob (2010) Sex-dependent effects of 56Fe irradiation on contextual fear conditioning in C57BL/6J mice. Hippocampus 20:19-23|
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