Northwestern University has participated in the NICHD Maternal Fetal Medicine Units Network for the last two cycles, and is applying to continue this participation through 2016. There are no substantial changes to the organization of our Center, with the principal investigator, both alternate principal investigators, and the research coordinator unchanged. Botii sites for our Center continue to have expanding clinical volume, making it one of the largest obstetric volume centers in the Network. We have a proven record of collaboration in clinical research both outside and within the Network. Our contributions over the last cycle have included not only high recruitment and data quality rankings, but also major contributions in protocol submissions and trial management.

Public Health Relevance

Despite significant efforts over the past two decades, rates of premature birth in the US have not decreased and remain major causes of perinatal morbidity. The MFMU Network will cooperate to perform research to identify optimal management strategies in this area, as well as in the area of medical complications of pregnancy. We have participated in trials such as the 17-P trial and the BEAM trial which have made major impacts on our field, and we look forward to the opportunity to continue with our contributions.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10HD040512-14
Application #
8442912
Study Section
Special Emphasis Panel (ZHD1-DRG-D (50))
Program Officer
Ilekis, John V
Project Start
2001-04-01
Project End
2016-03-31
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
14
Fiscal Year
2013
Total Cost
$285,233
Indirect Cost
$84,655
Name
Northwestern University at Chicago
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Peaceman, Alan M; Lai, Yinglei; Rouse, Dwight J et al. (2015) Length of latency with preterm premature rupture of membranes before 32 weeks' gestation. Am J Perinatol 32:57-62
Sutton, Amelia L; Mele, Lisa; Landon, Mark B et al. (2014) Delivery timing and cesarean delivery risk in women with mild gestational diabetes mellitus. Am J Obstet Gynecol 211:244.e1-7
Caritis, Steve N; Venkataramanan, Raman; Thom, Elizabeth et al. (2014) Relationship between 17-alpha hydroxyprogesterone caproate concentration and spontaneous preterm birth. Am J Obstet Gynecol 210:128.e1-6
Grobman, William A; Bailit, Jennifer L; Rice, Madeline Murguia et al. (2014) Frequency of and factors associated with severe maternal morbidity. Obstet Gynecol 123:804-10
Catalano, Patrick M; Mele, Lisa; Landon, Mark B et al. (2014) Inadequate weight gain in overweight and obese pregnant women: what is the effect on fetal growth? Am J Obstet Gynecol 211:137.e1-7
Graves, Steven W; Esplin, Michael S; McGee, Paula et al. (2014) Association of cord blood digitalis-like factor and necrotizing enterocolitis. Am J Obstet Gynecol 210:328.e1-5
Grobman, William A; Bailit, Jennifer L; Rice, Madeline Murguia et al. (2014) Can differences in obstetric outcomes be explained by differences in the care provided? The MFMU Network APEX study. Am J Obstet Gynecol 211:147.e1-147.e16
Sorokin, Yoram; Romero, Roberto; Mele, Lisa et al. (2014) Umbilical cord serum interleukin-6, C-reactive protein, and myeloperoxidase concentrations at birth and association with neonatal morbidities and long-term neurodevelopmental outcomes. Am J Perinatol 31:717-26
Figueroa, Dana; Landon, Mark B; Mele, Lisa et al. (2013) Relationship between 1-hour glucose challenge test results and perinatal outcomes. Obstet Gynecol 121:1241-7
Chiossi, Giuseppe; Lai, Yinglei; Landon, Mark B et al. (2013) Timing of delivery and adverse outcomes in term singleton repeat cesarean deliveries. Obstet Gynecol 121:561-9

Showing the most recent 10 out of 96 publications