Abstract

The central offices and administrative staff of the Vanderbilt Vaccine Center (VVC) will house the MIB Administrative Core, which will play a critical role in providing overall leadership and central administrative support of this Modeling Immunity for Biodefense (MIB) site. The Administrative Core aims to support the coordination of efforts across the component research projects and service core and to support activities to advance integration with the MIB consortium and the scientific community. One of the most vital functions of the Administrative Core will be communication between each of the organizational units within the MIB and with NIAID. The MIB Administrative Core will coordinate practical aspects of the program, which include communicating data and information, monitoring, and managing regulatory compliance. In addition, the MIB Administrative Core will be responsible for budgetary management of the program, preparing progress reports, travel arrangements, which include the MIB meetings, workshops, and symposia.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
1U19AI117905-01
Application #
8897069
Study Section
Special Emphasis Panel (ZAI1-QV-I (J3))
Project Start
Project End
2016-04-30
Budget Start
2015-05-01
Budget End
2016-04-30
Support Year
1
Fiscal Year
2015
Total Cost
$93,290
Indirect Cost
$18,345

  Institution

Name
Vanderbilt University Medical Center
Department
Type
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212

  Publications

Crowe Jr, James E (2018) Is It Possible to Develop a ""Universal"" Influenza Virus Vaccine? Potential for a Universal Influenza Vaccine. Cold Spring Harb Perspect Biol 10:
Bangaru, Sandhya; Zhang, Heng; Gilchuk, Iuliia M et al. (2018) A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA. Nat Commun 9:2669
Wijesinghe, Kaveesha J; Urata, Sarah; Bhattarai, Nisha et al. (2017) Detection of lipid-induced structural changes of the Marburg virus matrix protein VP40 using hydrogen/deuterium exchange-mass spectrometry. J Biol Chem 292:6108-6122
Crowe Jr, James E (2017) Principles of Broad and Potent Antiviral Human Antibodies: Insights for Vaccine Design. Cell Host Microbe 22:193-206
Bruhn, Jessica F; Kirchdoerfer, Robert N; Urata, Sarah M et al. (2017) Crystal Structure of the Marburg Virus VP35 Oligomerization Domain. J Virol 91:
Chandra, Vikas; Wu, Dalei; Li, Sheng et al. (2017) The quaternary architecture of RAR?-RXR? heterodimer facilitates domain-domain signal transmission. Nat Commun 8:868
Sangha, Amandeep K; Dong, Jinhui; Williamson, Lauren et al. (2017) Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein. Structure 25:1820-1828.e2
Labonte, Jason W; Adolf-Bryfogle, Jared; Schief, William R et al. (2017) Residue-centric modeling and design of saccharide and glycoconjugate structures. J Comput Chem 38:276-287
Tseng, Roger; Goularte, Nicolette F; Chavan, Archana et al. (2017) Structural basis of the day-night transition in a bacterial circadian clock. Science 355:1174-1180
Boyd, Scott D; Crowe Jr, James E (2016) Deep sequencing and human antibody repertoire analysis. Curr Opin Immunol 40:103-9

Showing the most recent 10 out of 24 publications