MIT and Harvard have excepfionally strong research and education programs in the biological/medical sciences on the one hand and in the physical/engineering sciences on the other, as well as strong programs in nanotechnology. There is a large pool of excellent students and MIT already has administrative and educational mechanisms in place for encouraging interdisciplinary activities among these students and the respective faculty members. We have structured our program to leverage this advantageous situation.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA151884-04
Application #
8547023
Study Section
Special Emphasis Panel (ZCA1-GRB-S)
Project Start
Project End
Budget Start
2013-08-01
Budget End
2014-07-31
Support Year
4
Fiscal Year
2013
Total Cost
$42,155
Indirect Cost
Name
Massachusetts Institute of Technology
Department
Type
DUNS #
001425594
City
Cambridge
State
MA
Country
United States
Zip Code
02139
Xiao, Zeyu (2014) CuS nanoparticles: clinically favorable materials for photothermal applications? Nanomedicine (Lond) 9:373-5
Zheng, Yao-Rong; Suntharalingam, Kogularamanan; Johnstone, Timothy C et al. (2014) Pt(IV) prodrugs designed to bind non-covalently to human serum albumin for drug delivery. J Am Chem Soc 136:8790-8
Wu, Jun; Kamaly, Nazila; Shi, Jinjun et al. (2014) Development of multinuclear polymeric nanoparticles as robust protein nanocarriers. Angew Chem Int Ed Engl 53:8975-9
Eltoukhy, Ahmed A; Sahay, Gaurav; Cunningham, James M et al. (2014) Niemann-Pick C1 affects the gene delivery efficacy of degradable polymeric nanoparticles. ACS Nano 8:7905-13
Lin, Kevin Y; Lo, Justin H; Consul, Nikita et al. (2014) Self-titrating anticoagulant nanocomplexes that restore homeostatic regulation of the coagulation cascade. ACS Nano 8:8776-85
Xue, Wen; Chen, Sidi; Yin, Hao et al. (2014) CRISPR-mediated direct mutation of cancer genes in the mouse liver. Nature 514:380-4
Morton, Stephen W; Zhao, Xiaoyong; Quadir, Mohiuddin A et al. (2014) FRET-enabled biological characterization of polymeric micelles. Biomaterials 35:3489-96
Chen, Ou; Riedemann, Lars; Etoc, Fred et al. (2014) Magneto-fluorescent core-shell supernanoparticles. Nat Commun 5:5093
Laughney, Ashley M; Kim, Eunha; Sprachman, Melissa M et al. (2014) Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin. Sci Transl Med 6:261ra152
Liu, Vincent H; Vassiliou, Christophoros C; Imaad, Syed M et al. (2014) Solid MRI contrast agents for long-term, quantitative in vivo oxygen sensing. Proc Natl Acad Sci U S A 111:6588-93

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