1.Center Administration - Provides Center Leadership &governance 2. Clinical Needs Assessment &Impact Analysis- Identifies clinical unmet needs in primary care;determines clinical and operational specifications for POC solutions. 3. Technical Innovation - Demonstrates technical proof-of-concept of proposed POC solution. 4. Clinical Validation - Demonstrates clinical proof-of-concept of proposed POC solution. 5. Commercial Acceleration - Demonstrates commercial proof-of-concept of proposed POC solution. 6. Education and Dissemination - Educates, trains and imparts knowledge on primary care unmet needs;on POC technology solutions;and the Center innovation process.

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54EB015408-02
Application #
8502259
Study Section
Special Emphasis Panel (ZEB1-OSR-D)
Project Start
Project End
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
2
Fiscal Year
2013
Total Cost
$1,798,336
Indirect Cost
$764,810
Name
Massachusetts General Hospital
Department
Type
DUNS #
073130411
City
Boston
State
MA
Country
United States
Zip Code
02199
Hassan, Umer; Watkins, Nicholas N; Reddy Jr, Bobby et al. (2016) Microfluidic differential immunocapture biochip for specific leukocyte counting. Nat Protoc 11:714-26
El Assal, Rami; Gurkan, Umut A; Chen, Pu et al. (2016) 3-D Microwell Array System for Culturing Virus Infected Tumor Cells. Sci Rep 6:39144
Asghar, Waseem; Yuksekkaya, Mehmet; Shafiee, Hadi et al. (2016) Engineering long shelf life multi-layer biologically active surfaces on microfluidic devices for point of care applications. Sci Rep 6:21163
Lifson, Mark A; Ozen, Mehmet Ozgun; Inci, Fatih et al. (2016) Advances in biosensing strategies for HIV-1 detection, diagnosis, and therapeutic monitoring. Adv Drug Deliv Rev 103:90-104
Wang, ShuQi; Chinnasamy, Thiruppathiraja; Lifson, Mark A et al. (2016) Flexible Substrate-Based Devices for Point-of-Care Diagnostics. Trends Biotechnol 34:909-921
Wang, ShuQi; Lifson, Mark A; Inci, Fatih et al. (2016) Advances in addressing technical challenges of point-of-care diagnostics in resource-limited settings. Expert Rev Mol Diagn 16:449-59
Rodriguez, Natalia M; Wong, Winnie S; Liu, Lena et al. (2016) A fully integrated paperfluidic molecular diagnostic chip for the extraction, amplification, and detection of nucleic acids from clinical samples. Lab Chip 16:753-63
Shafiee, Hadi; Wang, ShuQi; Inci, Fatih et al. (2015) Emerging technologies for point-of-care management of HIV infection. Annu Rev Med 66:387-405
Inci, Fatih; Filippini, Chiara; Baday, Murat et al. (2015) Multitarget, quantitative nanoplasmonic electrical field-enhanced resonating device (NE2RD) for diagnostics. Proc Natl Acad Sci U S A 112:E4354-63
Yildiz, U Hakan; Inci, Fatih; Wang, ShuQi et al. (2015) Recent advances in micro/nanotechnologies for global control of hepatitis B infection. Biotechnol Adv 33:178-90

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