1.Center Administration - Provides Center Leadership &governance 2. Clinical Needs Assessment &Impact Analysis- Identifies clinical unmet needs in primary care;determines clinical and operational specifications for POC solutions. 3. Technical Innovation - Demonstrates technical proof-of-concept of proposed POC solution. 4. Clinical Validation - Demonstrates clinical proof-of-concept of proposed POC solution. 5. Commercial Acceleration - Demonstrates commercial proof-of-concept of proposed POC solution. 6. Education and Dissemination - Educates, trains and imparts knowledge on primary care unmet needs;on POC technology solutions;and the Center innovation process.

National Institute of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Specialized Center--Cooperative Agreements (U54)
Project #
Application #
Study Section
Special Emphasis Panel (ZEB1-OSR-D)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Massachusetts General Hospital
United States
Zip Code
Liang, Li-Guo; Kong, Meng-Qi; Zhou, Sherry et al. (2017) An integrated double-filtration microfluidic device for isolation, enrichment and quantification of urinary extracellular vesicles for detection of bladder cancer. Sci Rep 7:46224
Liang, Li-Guo; Sheng, Ye-Feng; Zhou, Sherry et al. (2017) An Integrated Double-Filtration Microfluidic Device for Detection of Extracellular Vesicles from Urine for Bladder Cancer Diagnosis. Methods Mol Biol 1660:355-364
Batsis, John A; Pletcher, Sarah N; Stahl, James E (2017) Telemedicine and primary care obesity management in rural areas - innovative approach for older adults? BMC Geriatr 17:6
Sher, Mazhar; Zhuang, Rachel; Demirci, Utkan et al. (2017) Paper-based analytical devices for clinical diagnosis: recent advances in the fabrication techniques and sensing mechanisms. Expert Rev Mol Diagn 17:351-366
Sauer-Budge, Alexis F; Brookfield, Samuel J; Janzen, Ronald et al. (2017) A novel device for collecting and dispensing fingerstick blood for point of care testing. PLoS One 12:e0183625
Rodriguez, Natalia M; Wong, Winnie S; Liu, Lena et al. (2016) A fully integrated paperfluidic molecular diagnostic chip for the extraction, amplification, and detection of nucleic acids from clinical samples. Lab Chip 16:753-63
Lifson, Mark A; Ozen, Mehmet Ozgun; Inci, Fatih et al. (2016) Advances in biosensing strategies for HIV-1 detection, diagnosis, and therapeutic monitoring. Adv Drug Deliv Rev 103:90-104
Wang, ShuQi; Lifson, Mark A; Inci, Fatih et al. (2016) Advances in addressing technical challenges of point-of-care diagnostics in resource-limited settings. Expert Rev Mol Diagn 16:449-59
Wang, Chien-Chung; Hennek, Jonathan W; Ainla, Alar et al. (2016) A Paper-Based ""Pop-up"" Electrochemical Device for Analysis of Beta-Hydroxybutyrate. Anal Chem 88:6326-33
El Assal, Rami; Gurkan, Umut A; Chen, Pu et al. (2016) 3-D Microwell Array System for Culturing Virus Infected Tumor Cells. Sci Rep 6:39144

Showing the most recent 10 out of 45 publications