Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54GM094611-04
Application #
8536327
Study Section
Special Emphasis Panel (ZGM1-CBB-3)
Project Start
Project End
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
4
Fiscal Year
2013
Total Cost
$213,649
Indirect Cost
$51,117
Name
Hauptman-Woodward Medical Research Institute
Department
Type
DUNS #
074025479
City
Buffalo
State
NY
Country
United States
Zip Code
14203
Coudray, Nicolas; L Seyler, Sean; Lasala, Ralph et al. (2016) Structure of the SLC4 transporter Bor1p in an inward-facing conformation. Protein Sci :
Coudray, Nicolas; Lasala, Ralph; Zhang, Zhening et al. (2016) Deducing the symmetry of helical assemblies: Applications to membrane proteins. J Struct Biol 195:167-78
Otsuka, Taketo; Kirkham, Charmaine; Brauer, Aimee et al. (2016) The Vaccine Candidate Substrate Binding Protein SBP2 Plays a Key Role in Arginine Uptake, Which Is Required for Growth of Moraxella catarrhalis. Infect Immun 84:432-8
Clark, Kathleen M; Jenkins, Jermaine L; Fedoriw, Nadia et al. (2016) Human CaaX Protease ZMPSTE24 Expressed in Yeast: Structure and Inhibition by HIV Protease Inhibitors. Protein Sci :
Mathew, Elizabeth; Dumont, Mark E (2015) A Novel Screening Approach for Optimal and Functional Fusion of T4 Lysozyme in GPCRs. Methods Enzymol 557:27-43
Zuber, Jeffrey; Danial, Shairy Azmy; Connelly, Sara M et al. (2015) Identification of destabilizing and stabilizing mutations of Ste2p, a G protein-coupled receptor in Saccharomyces cerevisiae. Biochemistry 54:1787-806
Bauer, William J; Luthra, Amit; Zhu, Guangyu et al. (2015) Structural characterization and modeling of the Borrelia burgdorferi hybrid histidine kinase Hk1 periplasmic sensor: A system for sensing small molecules associated with tick feeding. J Struct Biol 192:48-58
Zhu, Guangyu; Koszelak-Rosenblum, Mary; Connelly, Sara M et al. (2015) The Crystal Structure of an Integral Membrane Fatty Acid α-Hydroxylase. J Biol Chem 290:29820-33
Anand, Arvind; LeDoyt, Morgan; Karanian, Carson et al. (2015) Bipartite Topology of Treponema pallidum Repeat Proteins C/D and I: OUTER MEMBRANE INSERTION, TRIMERIZATION, AND PORIN FUNCTION REQUIRE A C-TERMINAL β-BARREL DOMAIN. J Biol Chem 290:12313-31
Jones, Megan M; Johnson, Antoinette; Koszelak-Rosenblum, Mary et al. (2014) Role of the oligopeptide permease ABC Transporter of Moraxella catarrhalis in nutrient acquisition and persistence in the respiratory tract. Infect Immun 82:4758-66

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