EH&BRR is an extension of UTMB Environmental Health and Safety (EHS) and as such provides critical health, safety, and training services;maintains consistency in biosafety and biocontainment practices; provides biosafety theory education and hands-on training in conjunction with the National Biocontainment Training Center. The Core implements all of the requirements for possession, use and storage of select agents and toxins stipulated by 42 CFR 73 National Select Agent Registration Program. EH&BRR staff continuously maintain and monitor the integrity of the BSL4 containment areas;provide expertise in areas of primary containment operations;lead decontamination, retesting, and support the maintenance and certification of BSL4 containment facilities. The Core responds to potential emergency events and plans for the orderly shutdown and decontamination of containment due to weather or other events. The primary objective for the Environmental Health and Biosafety Regulations and Requirements Core is to continue to ensure that the GNL is fully compliant with all select agent, safety and security regulations, and university requirements and that the facility is well prepared for all adverse weather or other events.
The EH&BRR core provides essential support to meet local, state and federal regulations, including environmental health and safety aspects of biological, chemical and radiological protection, hazardous waste management, occupational health, and fire safety. The core coordinates research across institutional committees and provides training to individuals involved in high and maximum containment labs.
|Patterson, Michael; Seregin, Alexey; Huang, Cheng et al. (2014) Rescue of a recombinant Machupo virus from cloned cDNAs and in vivo characterization in interferon (**/ýý) receptor double knockout mice. J Virol 88:1914-23|
|Thangamani, Saravanan; Bente, Dennis (2014) Establishing protocols for tick containment at Biosafety Level 4. Pathog Dis 71:282-5|
|Hermance, Meghan E; Thangamani, Saravanan (2014) Proinflammatory cytokines and chemokines at the skin interface during Powassan virus transmission. J Invest Dermatol 134:2280-3|
|Yun, Nadezhda E; Seregin, Alexey V; Walker, David H et al. (2013) Mice lacking functional STAT1 are highly susceptible to lethal infection with Lassa virus. J Virol 87:10908-11|