The University of Texas Health Science Center at Houston (UTHSC-H), The University of Texas M.D. Anderson Cancer Center (UT MDACC), and the Memorial Hermann Hospital System wish to renew their Clinical and Translational Science Award (CTSA), which established the Center for Clinical and Translational Sciences (CCTS) in 2006. In the first cycle, the institutions created our CCTS, provided services to 835 investigators in 104 fields, trained KL2 scholars and TL1 trainees, and worked with the greater Houston and Brownsville communities to disseminate health care information and study the unique health issues in Brownsville's Hispanic border population. To further collaborative research in Texas, our CCTS founded the Texas CTSA Consortium and the Lowering the Barriers Program, which has established IRB reciprocity in the University of Texas System. Our CCTS's mission reads: The Center for Clinical and Translational Sciences provides research infrastructure, training and knowledge transfer to expedite the process of translating discovery to practice. We faciliate research and its dissemination for our investigators, our trainees and students, our patients, our local and state population, our Texas CTSA consortium collaborators, and the national CTSA consortium. To this end, we will focus on a thematic structure in the next cycle. Our themes are: 1) Advancing Translational Sciences by Advancing Personalized Therapy (T1 translation) by determing pathophysiology and developing targeted therapeutics and Advancing Community Engagement and dissemination and implementation research (T3/T4 translation); 2) Advancing Clinical Sciences by accelerating and improving new modalities for the design and conduct of clinical research and by accelerating and improving outcomes of research (T2 translation); and 3) Advancing the Clinical and Translational Science Research Workforce (Post-graduate training. Graduate training and research staff training).

Public Health Relevance

The goal of the Center for Clinical and Translational Sciences (CCTS), funded by a Clinical and Translational Science Award, is to move scientific and medical discoveries as fas as possible from the laboratory to the clinic and community, where they can improve the health of the American people. The CCTS trains researchers, provides research services, and works with its communities to learn their helath concerns and spread health care information.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
4UL1TR000371-10
Application #
9114185
Study Section
Special Emphasis Panel (ZRR1)
Program Officer
Merchant, Carol
Project Start
2006-07-01
Project End
2017-05-31
Budget Start
2016-06-01
Budget End
2017-05-31
Support Year
10
Fiscal Year
2016
Total Cost
Indirect Cost
Name
University of Texas Health Science Center Houston
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
800771594
City
Houston
State
TX
Country
United States
Zip Code
77225
Perales, Joseph; Reininger, Belinda M; Lee, MinJae et al. (2018) Participants' perceptions of interactions with community health workers who promote behavior change: a qualitative characterization from participants with normal, depressive and anxious mood states. Int J Equity Health 17:19
Artime, Carlos A; Aijazi, Hassan; Zhang, Haijun et al. (2018) Scheduled Intravenous Acetaminophen Improves Patient Satisfaction With Postcraniotomy Pain Management: A Prospective, Randomized, Placebo-controlled, Double-blind Study. J Neurosurg Anesthesiol 30:231-236
Sakamuri, Divya; Glitza, Isabella C; Betancourt Cuellar, Sonia L et al. (2018) Phase I Dose-Escalation Study of Anti-CTLA-4 Antibody Ipilimumab and Lenalidomide in Patients with Advanced Cancers. Mol Cancer Ther 17:671-676
Keene, Kimberly S; King, Tari; Hwang, E Shelley et al. (2018) Molecular determinants of post-mastectomy breast cancer recurrence. NPJ Breast Cancer 4:34
Callegari, Keri; Maegawa, Shinji; Bravo-Alegria, Javiera et al. (2018) Pharmacological inhibition of LSD1 activity blocks REST-dependent medulloblastoma cell migration. Cell Commun Signal 16:60
Meric-Bernstam, Funda; Zheng, Xiaofeng; Shariati, Maryam et al. (2018) Survival Outcomes by TP53 Mutation Status in Metastatic Breast Cancer. JCO Precis Oncol 2018:
Rahbar, Mohammad H; Choi, Sangbum; Hong, Chuan et al. (2018) Nonparametric estimation of median survival times with applications to multi-site or multi-center studies. PLoS One 13:e0197295
Miao, Yi-Feng; Peng, Tao; Moody, Melanie R et al. (2018) Delivery of xenon-containing echogenic liposomes inhibits early brain injury following subarachnoid hemorrhage. Sci Rep 8:450
Lee, MinJae; Rahbar, Mohammad H; Brown, Matthew et al. (2018) A multiple imputation method based on weighted quantile regression models for longitudinal censored biomarker data with missing values at early visits. BMC Med Res Methodol 18:8
Harvin, John A; Wootton, Susan H; Miller, Charles C (2018) Using Quality Improvement to Promote Clinical Trials of Emergency Trauma Therapies. JAMA 320:1855-1856

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