The University of Texas Health Science Center at Houston (UTHSC-H), The University of Texas M.D. Anderson Cancer Center (UT MDACC), and the Memorial Hermann Hospital System wish to renew their Clinical and Translational Science Award (CTSA), which established the Center for Clinical and Translational Sciences (CCTS) in 2006. In the first cycle, the institutions created our CCTS, provided services to 835 investigators in 104 fields, trained KL2 scholars and TL1 trainees, and worked with the greater Houston and Brownsville communities to disseminate health care information and study the unique health issues in Brownsville's Hispanic border population. To further collaborative research in Texas, our CCTS founded the Texas CTSA Consortium and the Lowering the Barriers Program, which has established IRB reciprocity in the University of Texas System. Our CCTS's mission reads: The Center for Clinical and Translational Sciences provides research infrastructure, training and knowledge transfer to expedite the process of translating discovery to practice. We faciliate research and its dissemination for our investigators, our trainees and students, our patients, our local and state population, our Texas CTSA consortium collaborators, and the national CTSA consortium. To this end, we will focus on a thematic structure in the next cycle. Our themes are: 1) Advancing Translational Sciences by Advancing Personalized Therapy (T1 translation) by determing pathophysiology and developing targeted therapeutics and Advancing Community Engagement and dissemination and implementation research (T3/T4 translation); 2) Advancing Clinical Sciences by accelerating and improving new modalities for the design and conduct of clinical research and by accelerating and improving outcomes of research (T2 translation); and 3) Advancing the Clinical and Translational Science Research Workforce (Post-graduate training. Graduate training and research staff training).

Public Health Relevance

The goal of the Center for Clinical and Translational Sciences (CCTS), funded by a Clinical and Translational Science Award, is to move scientific and medical discoveries as fas as possible from the laboratory to the clinic and community, where they can improve the health of the American people. The CCTS trains researchers, provides research services, and works with its communities to learn their helath concerns and spread health care information.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
2UL1TR000371-06A1
Application #
8462758
Study Section
Special Emphasis Panel (ZRR1-CR-1 (01))
Program Officer
Merchant, Carol
Project Start
2006-07-01
Project End
2017-05-31
Budget Start
2012-06-27
Budget End
2013-05-31
Support Year
6
Fiscal Year
2012
Total Cost
$2,759,336
Indirect Cost
$440,687
Name
University of Texas Health Science Center Houston
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
800771594
City
Houston
State
TX
Country
United States
Zip Code
77225
Rianon, Nahid; Ambrose, Catherine G; Buni, Maryam et al. (2018) Trabecular Bone Score Is a Valuable Addition to Bone Mineral Density for Bone Quality Assessment in Older Mexican American Women With Type 2 Diabetes. J Clin Densitom 21:355-359
Dau, Jonathan D; Lee, MinJae; Ward, Michael M et al. (2018) Opioid Analgesic Use in Patients with Ankylosing Spondylitis: An Analysis of the Prospective Study of Outcomes in an Ankylosing Spondylitis Cohort. J Rheumatol 45:188-194
Kono, Miho; Fujii, Takeo; Matsuda, Naoko et al. (2018) Somatic mutations, clinicopathologic characteristics, and survival in patients with untreated breast cancer with bone-only and non-bone sites of first metastasis. J Cancer 9:3640-3646
Cai, Chunyan; Piao, Jin; Ning, Jing et al. (2018) Efficient two-stage designs and proper inference for animal studies. Stat Biosci 10:217-232
Cherla, Deepa V; Viso, Cristina P; Olavarria, Oscar A et al. (2018) The Impact of Financial Conflict of Interest on Surgical Research: An Observational Study of Published Manuscripts. World J Surg 42:2757-2762
Watt, Gordon P; Lee, Miryoung; Pan, Jen-Jung et al. (2018) High Prevalence of Hepatic Fibrosis, Measured by Elastography, in a Population-Based Study of Mexican Americans. Clin Gastroenterol Hepatol :
Sanner, Jennifer; Grove, Megan L; Yu, Erica et al. (2018) Effects of Gender-Specific Differences, Inflammatory Response, and Genetic Variation on the Associations Among Depressive Symptoms and the Risk of Major Adverse Coronary Events in Patients With Acute Coronary Syndrome. Biol Res Nurs 20:168-176
Sen, Shiraj; Hess, Kenneth; Hong, David S et al. (2018) Development of a prognostic scoring system for patients with advanced cancer enrolled in immune checkpoint inhibitor phase 1 clinical trials. Br J Cancer 118:763-769
Drilon, Alexander; Laetsch, Theodore W; Kummar, Shivaani et al. (2018) Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children. N Engl J Med 378:731-739
You, Yanan; Cuevas-Diaz Duran, Raquel; Jiang, Lihua et al. (2018) An integrated global regulatory network of hematopoietic precursor cell self-renewal and differentiation. Integr Biol (Camb) 10:390-405

Showing the most recent 10 out of 683 publications