To address the CTSA vision to have a sustained and transformative influence on the quality and value of clinical &translational research, leadership from three academic institutions - Emory University, Morehouse School of Medicine, and Georgia Institute of Technology, along with other collaborative organizations formed in 2007, the Atlanta Clinical and Translational Science Institute (ACTSI). The ACTSI has integrated discovery, education, training and community engagement programs and engendered an unprecedented level of transformation in clinical and translational research in our community. The ACTSI has developed an Atlanta """"""""home"""""""" for clinical and translational research through support of: 673 investigators, 520 projects, 93 pilot projects in 96 research areas, over 193 federal (PHS) grants, 134 current or graduated MSCR, KL, or TL scholars, and over 75 additional active trainees. ACTSI support has also contributed to 661 scientific publications, tripled inter-institutional collaborations, and led to important scientific breakthroughs in clinical and translational science. Guided by the mission, """"""""[tjhrough ethical community engagement, focused education and training, and innovative,support of discovery, the collaborative partners ofthe ACTSI rapidly and efficiently translate scientific discoveries to impact all populations ofthe Atlanta community,"""""""" in the next five years, eleven key function prograrns will be charged with implementing three expanded specific aims.
Aim 1 : Promote discovery through inter-disciplinary collaboration, the development of novel and emerging technologies, drugs, devices, diagnostics and biologies, and the efficient translation of these discoveries to benefit human health.
Aim 2 : Expand and improve outstanding programs to educate and train a growing cadre of ethnically diverse, clinician scientists, and increase the capacity and infrastructure to foster multidisciplinary translational researchIteams.
Aim 3 : Actively engage the community in research that will engender the public trust in scientific discovery and the translation of new knowledge that ultimately enhances the health ofthe communities we serve.

Public Health Relevance

Created in tespohse to the NIH CTSA program, the Atlanta CTSI serves as a catalyst and incubator for clinical and ti""""""""anslational research across Georgia and with regional and national impact. The goals are to create and accelerate clinical and translational science discovery, build interdisciplinary research capacity, engage communities in health sciences activities, develop new research tools and information technologies, and build the careers of clinical/translational scientists ofthe future.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
5UL1TR000454-07
Application #
8499475
Study Section
Special Emphasis Panel (ZRR1-CR-1 (01))
Program Officer
Rosenblum, Daniel
Project Start
2007-09-17
Project End
2017-05-31
Budget Start
2013-06-01
Budget End
2014-05-31
Support Year
7
Fiscal Year
2013
Total Cost
$4,839,297
Indirect Cost
$619,319
Name
Emory University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
066469933
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Warren-Jeanpiere, Lari; Dillaway, Heather; Hamilton, Pilar et al. (2017) Life begins at 60: Identifying the social support needs of African American women aging with HIV. J Health Care Poor Underserved 28:389-405
Routledge, Faye S; Dunbar, Sandra B; Higgins, Melinda et al. (2017) Insomnia Symptoms Are Associated With Abnormal Endothelial Function. J Cardiovasc Nurs 32:78-85
Edwards, Erin Elizabeth; Thomas, Susan Napier (2017) P-Selectin and ICAM-1 synergy in mediating THP-1 monocyte adhesion in hemodynamic flow is length dependent. Integr Biol (Camb) 9:313-327
Mehanna, Mai; Gong, Yan; McDonough, Caitrin W et al. (2017) Blood pressure response to metoprolol and chlorthalidone in European and African Americans with hypertension. J Clin Hypertens (Greenwich) 19:1301-1308
Tangpricha, Vin; Smith, Ellen M; Binongo, Jose et al. (2017) The Vitamin D for Enhancing the Immune System in Cystic Fibrosis (DISC) trial: Rationale and design of a multi-center, double-blind, placebo-controlled trial of high dose bolus administration of vitamin D3 during acute pulmonary exacerbation of cystic fib Contemp Clin Trials Commun 6:39-45
Wang, Bin; Zhang, Cong; Zhang, Aiqing et al. (2017) MicroRNA-23a and MicroRNA-27a Mimic Exercise by Ameliorating CKD-Induced Muscle Atrophy. J Am Soc Nephrol 28:2631-2640
Scherzer, Rebecca; Greenblatt, Ruth M; Merhi, Zaher O et al. (2017) Use of antim├╝llerian hormone to predict the menopausal transition in HIV-infected women. Am J Obstet Gynecol 216:46.e1-46.e11
Nabi, Rafiq; Moldoveanu, Zina; Wei, Qing et al. (2017) Differences in serum IgA responses to HIV-1 gp41 in elite controllers compared to viral suppressors on highly active antiretroviral therapy. PLoS One 12:e0180245
Han, Jenny E; Alvarez, Jessica A; Staitieh, Bashar et al. (2017) Oxidative stress in critically ill ventilated adults: effects of vitamin D3 and associations with alveolar macrophage function. Eur J Clin Nutr :
Vergara, C; Thio, C; Latanich, R et al. (2017) Genetic basis for variation in plasma IL-18 levels in persons with chronic hepatitis C virus and human immunodeficiency virus-1 infections. Genes Immun 18:82-87

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