Diet and other early exposures may affect child development and the risk of several chronic diseases, but additional research is needed. The current research described in this catch-all project comprises one project, described below. We examined physical activity during pregnancy in relation to neurodevelopment in offspring, based on data from the Avon Longitudinal Study of Parents and Children. As would be predicted on the basis of results in animal experiments, if the mother excercised during pregnancy the children's early language development was improved, independently of measured confounding factors. A report was published. We examined in utero exposure to maternal tobacco smoking in relation to subsequent gestational diabetes when the women became adults. In utero exposure was associated with an increased risk of gestational diabetes, confirming a finding that we observed in the Norwegian Mother and Child Cohort Study. A report was published.

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Jensen, Elizabeth T; Longnecker, Matthew P (2014) Pharmacologic sex hormones in pregnancy in relation to offspring obesity. Obesity (Silver Spring) 22:2406-12
Trabert, Britton; Chodick, Gabriel; Shalev, Varda et al. (2014) Gestational diabetes and the risk of cryptorchidism and hypospadias. Epidemiology 25:152-3
Jukic, Anne Marie Z; Lawlor, Debbie A; Juhl, Mette et al. (2013) Physical activity during pregnancy and language development in the offspring. Paediatr Perinat Epidemiol 27:283-93
Nepomnaschy, Pablo A; Baird, Donna Day; Weinberg, Clarice R et al. (2009) Within-person variability in urinary bisphenol A concentrations: measurements from specimens after long-term frozen storage. Environ Res 109:734-7
Ye, Xibiao; Qian, Haojun; Xu, Peicheng et al. (2009) Nephrotoxicity, neurotoxicity, and mercury exposure among children with and without dental amalgam fillings. Int J Hyg Environ Health 212:378-86
Baird, Donna Day; Saldana, Tina M; Nepomnaschy, Pablo A et al. (2009) Within-person variability in urinary phthalate metabolite concentrations: measurements from specimens after long-term frozen storage. J Expo Sci Environ Epidemiol :
Windham, Gayle C; Zhang, Lixia; Longnecker, Matthew P et al. (2008) Maternal smoking, demographic and lifestyle factors in relation to daughter's age at menarche. Paediatr Perinat Epidemiol 22:551-61
Arbuckle, Tye E; Hauser, Russ; Swan, Shanna H et al. (2008) Meeting report: measuring endocrine-sensitive endpoints within the first years of life. Environ Health Perspect 116:948-51