Biomedical engineering has the mission of combining the quantitative analysis and technological innovation of engineering with the modern advances of biomedical sciences to generate new scientific knowledge and advance health care. The UCSD is uniquely situated to provide leadership in biomedical engineering due to its existing strengths in both education and research at the advancing frontiers of engineering and biomedical sciences. UCSD Bioengineering has adopted the overall theme of Integrative Bioengineering, which includes the integration of research activities at all levels of biomedical engineering design from genes to molecules to the whole organism, interaction between engineering and biomedical sciences, coordination of research and education, partnerships between UCSD with its neighboring institutions, and collaboration with industry and clinical medicine for effective technology transfer. UCSD Bioengineering is leveraging on its existing strengths in biomechanics, cardiovascular physiology, microcirculation, tissue engineering, and cellular and molecular biology to develop new initiatives in research and education. The new Powell-Focht Bioengineering Hall under construction on UCSD's campus will serve as a platform for these activities. Molecular Biomechanics, Cell-Matrix Engineering, and Cardiac Systems Engineering are new research areas and faculty recruitments in these areas are underway. The present application is for funds to build out three research laboratories for these activities and a nanotechnology core space in presently shelled space in the new building. This is necessary to develop biomedical engineering at UCSD to its full potential and to provide a model of bioengineering education and research for the nation.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Research Facilities Construction Grant (C06)
Project #
1C06RR017588-01
Application #
6794501
Study Section
Scientific and Technical Review Board on Biomedical and Behavioral Research Facilities (STRB)
Project Start
2002-09-15
Project End
2003-09-14
Budget Start
2002-09-15
Budget End
2003-09-14
Support Year
1
Fiscal Year
2002
Total Cost
$174,000
Indirect Cost
Name
University of California San Diego
Department
Biomedical Engineering
Type
Schools of Arts and Sciences
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Kerckhoffs, Roy C P (2012) Computational modeling of cardiac growth in the post-natal rat with a strain-based growth law. J Biomech 45:865-71
Campbell, Stuart G; Lionetti, Fred V; Campbell, Kenneth S et al. (2010) Coupling of adjacent tropomyosins enhances cross-bridge-mediated cooperative activation in a markov model of the cardiac thin filament. Biophys J 98:2254-64
Kerckhoffs, Roy C P; Omens, Jeffrey H; McCulloch, Andrew D et al. (2010) Ventricular dilation and electrical dyssynchrony synergistically increase regional mechanical nonuniformity but not mechanical dyssynchrony: a computational model. Circ Heart Fail 3:528-36
Han, Buhm; Kang, Hyun Min; Eskin, Eleazar (2009) Rapid and accurate multiple testing correction and power estimation for millions of correlated markers. PLoS Genet 5:e1000456
Zaitlen, Noah; Kang, Hyun Min; Eskin, Eleazar (2009) Linkage effects and analysis of finite sample errors in the HapMap. Hum Hered 68:73-86
Campbell, Stuart G; Howard, Elliot; Aguado-Sierra, Jazmin et al. (2009) Effect of transmurally heterogeneous myocyte excitation-contraction coupling on canine left ventricular electromechanics. Exp Physiol 94:541-52
Kerckhoffs, Roy C P; McCulloch, Andrew D; Omens, Jeffrey H et al. (2009) Effects of biventricular pacing and scar size in a computational model of the failing heart with left bundle branch block. Med Image Anal 13:362-9
Kerckhoffs, Roy C P; Campbell, Stuart G; Flaim, Sarah N et al. (2009) Multi-scale modeling of excitation-contraction coupling in the normal and failing heart. Conf Proc IEEE Eng Med Biol Soc 2009:4281-2
Kerckhoffs, R C P; Lumens, J; Vernooy, K et al. (2008) Cardiac resynchronization: insight from experimental and computational models. Prog Biophys Mol Biol 97:543-61
Kang, Hyun Min; Zaitlen, Noah A; Wade, Claire M et al. (2008) Efficient control of population structure in model organism association mapping. Genetics 178:1709-23

Showing the most recent 10 out of 22 publications