Schistosomiasis is a re-emerging disease as its incidence has increased in humans over the past decade. It currently afflicts some 200 million individuals in 76 countries of the world. Its main impact is to dehabilitate populations although 800,000 people succumb to the disease. This training grant will strengthen our current research program in Brazil and allow us to build sustainable research capacity at the Centro des Pesquisas Rene Rachou, FIOCRUZ by establishing research programs in genetic epidemiologic and geographic information systems to enhance ongoing immunological field research, strengthen existing programs in immunology, bioinformatics and interest established American scientists in emerging and reemerging diseases. We propose long-term training of 4 postdoctoral fellows, two years each, mid- and short-term training coupled with workshops to have an immediate impact on our research and to attract the interest of the Brazilian scientific community. This training grant is expected to strengthen the capacity of American and Brazilian scientists associated with the Centro des Pesquisas Rene Rachou and the International Center for Infectious Diseases Research Program through studies on schistosomiasis to understand and respond to a reemerging infectious disease and with further training to outbreaks of any infectious disease. ?
| Scholte, Ronaldo G C; Freitas, Corina C; Dutra, Luciano V et al. (2012) Utilizing environmental, socioeconomic data and GIS techniques to estimate the risk for ascariasis and trichuriasis in Minas Gerais, Brazil. Acta Trop 121:112-7 |
| Simões, Mariana C; Lee, Jonathan; Djikeng, Appolinaire et al. (2011) Identification of Schistosoma mansoni microRNAs. BMC Genomics 12:47 |
| Kloos, Helmut; Correa-Oliveira, Rodrigo; dos Reis, Dener Carlos et al. (2010) The role of population movement in the epidemiology and control of schistosomiasis in Brazil: a preliminary typology of population movement. Mem Inst Oswaldo Cruz 105:578-86 |
| Carvalho, Omar S; Scholte, Ronaldo G C; Guimaraes, Ricardo J P S et al. (2010) The Estrada Real project and endemic diseases: the case of schistosomiasis, geoprocessing and tourism. Mem Inst Oswaldo Cruz 105:532-6 |
| Reis, Dener Carlos dos; Kloos, Helmut; King, Charles et al. (2010) Accessibility to and utilisation of schistosomiasis-related health services in a rural area of state of Minas Gerais, Brazil. Mem Inst Oswaldo Cruz 105:587-97 |
| Pereira, Wesley Rodrigues; Kloos, Helmut; Crawford, Sara B et al. (2010) Schistosoma mansoni infection in a rural area of the Jequitinhonha Valley, Minas Gerais, Brazil: analysis of exposure risk. Acta Trop 113:34-41 |
| Berriman, Matthew; Haas, Brian J; LoVerde, Philip T et al. (2009) The genome of the blood fluke Schistosoma mansoni. Nature 460:352-8 |
| Valentim, Claudia L L; LoVerde, Philip T; Anderson, Timothy J C et al. (2009) Efficient genotyping of Schistosoma mansoni miracidia following whole genome amplification. Mol Biochem Parasitol 166:81-4 |
| Criscione, Charles D; Valentim, Claudia L L; Hirai, Hirohisa et al. (2009) Genomic linkage map of the human blood fluke Schistosoma mansoni. Genome Biol 10:R71 |
| Kloos, Helmut; Correa-Oliveira, Rodrigo; Oliveira Quites, Humberto Ferreira et al. (2008) Socioeconomic studies of schistosomiasis in Brazil: a review. Acta Trop 108:194-201 |
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