Agency
National Institute of Health (NIH)
Institute
Office of The Director, National Institutes of Health (OD)
Type
NIH Director’s New Innovator Awards (DP2)
Project #
1DP2OD002980-01
Application #
7432044
Study Section
Special Emphasis Panel (ZGM1-NDIA-G (03))
Program Officer
Basavappa, Ravi
Project Start
2007-09-30
Project End
2012-08-31
Budget Start
2007-09-30
Budget End
2012-08-31
Support Year
1
Fiscal Year
2007
Total Cost
$2,481,250
Indirect Cost
Name
Yale University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520
Xu, Yingke; Toomre, Derek K; Bogan, Jonathan S et al. (2017) Excess cholesterol inhibits glucose-stimulated fusion pore dynamics in insulin exocytosis. J Cell Mol Med 21:2950-2962
Kukic, Ira; Rivera-Molina, Felix; Toomre, Derek (2016) The IN/OUT assay: a new tool to study ciliogenesis. Cilia 5:23
Erdmann, Roman S; Takakura, Hideo; Thompson, Alexander D et al. (2014) Super-resolution imaging of the Golgi in live cells with a bioorthogonal ceramide probe. Angew Chem Int Ed Engl 53:10242-6
Rivera-Molina, Felix; Toomre, Derek (2013) Live-cell imaging of exocyst links its spatiotemporal dynamics to various stages of vesicle fusion. J Cell Biol 201:673-80
Zhang, Yong; Tang, Wenwen; Zhang, Haifeng et al. (2013) A network of interactions enables CCM3 and STK24 to coordinate UNC13D-driven vesicle exocytosis in neutrophils. Dev Cell 27:215-226
Arasaki, Kohei; Toomre, Derek K; Roy, Craig R (2012) The Legionella pneumophila effector DrrA is sufficient to stimulate SNARE-dependent membrane fusion. Cell Host Microbe 11:46-57
Tkachenko, Eugene; Tse, Dan; Sideleva, Olga et al. (2012) Caveolae, fenestrae and transendothelial channels retain PV1 on the surface of endothelial cells. PLoS One 7:e32655
Xu, Yingke; Rubin, Bradley R; Orme, Charisse M et al. (2011) Dual-mode of insulin action controls GLUT4 vesicle exocytosis. J Cell Biol 193:643-53
Xu, Yingke; Melia, Thomas J; Toomre, Derek K (2011) Using light to see and control membrane traffic. Curr Opin Chem Biol 15:822-30
Liang, Liang; Shen, Hongying; De Camilli, Pietro et al. (2011) An expectation maximization based method for subcellular particle tracking using multi-angle TIRF microscopy. Med Image Comput Comput Assist Interv 14:629-36

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