Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
International Research Fellowships (FIC) (F05)
Project #
1F05TW003742-01
Application #
3020995
Study Section
(BI)
Project Start
1987-07-07
Project End
Budget Start
1986-08-15
Budget End
1987-08-14
Support Year
1
Fiscal Year
1986
Total Cost
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Type
Overall Medical
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Leitersdorf, E; Luskey, K L (1990) HgiAI polymorphism near the HMGCR promoter. Nucleic Acids Res 18:5584
Leitersdorf, E; Tobin, E J; Davignon, J et al. (1990) Common low-density lipoprotein receptor mutations in the French Canadian population. J Clin Invest 85:1014-23
Leitersdorf, E; Hwang, M; Luskey, K L (1990) ScrFI polymorphism in the 2nd intron of the HMGCR gene. Nucleic Acids Res 18:5584
Leitersdorf, E; Chakravarti, A; Hobbs, H H (1989) Polymorphic DNA haplotypes at the LDL receptor locus. Am J Hum Genet 44:409-21
Leitersdorf, E; Van der Westhuyzen, D R; Coetzee, G A et al. (1989) Two common low density lipoprotein receptor gene mutations cause familial hypercholesterolemia in Afrikaners. J Clin Invest 84:954-61
Hobbs, H H; Leitersdorf, E; Leffert, C C et al. (1989) Evidence for a dominant gene that suppresses hypercholesterolemia in a family with defective low density lipoprotein receptors. J Clin Invest 84:656-64
Leitersdorf, E; Hobbs, H H; Fourie, A M et al. (1988) Deletion in the first cysteine-rich repeat of low density lipoprotein receptor impairs its transport but not lipoprotein binding in fibroblasts from a subject with familial hypercholesterolemia. Proc Natl Acad Sci U S A 85:7912-6
Hobbs, H H; Leitersdorf, E; Goldstein, J L et al. (1988) Multiple crm- mutations in familial hypercholesterolemia. Evidence for 13 alleles, including four deletions. J Clin Invest 81:909-17
Leitersdorf, E; Hobbs, H H (1987) Human LDL receptor gene: two ApaLI RFLPs. Nucleic Acids Res 15:2782