There are over 2.4 million breast cancer survivors (BCS) in the U.S. accounting for 22% of all cancer survivors [1]. The 5-year survival rate of 88.6% [1] coupled with a 1 in 8 lifetime chance of a breast cancer diagnosis [2] has resulted in an increasingly growing population with distinct public health needs resulting from side effects associated with current available treatments [3]. In addition, BCS are at an increased risk of cancer recurrence, comborbidites, premature death and decreased quality of life (QOL) [4-6]. Physical activity (PA) has been identified as a lifestyle factor with excellent potential for ameliorating the aversive side effects of treatment and positively influencing disease-related outcomes [7, 8]. However, only 1/3 of BCS meet the current public health guidelines for PA [9, 10]. Identifying factors influencing PA participation and how PA is related to QOL in BCS is important for developing effective interventions which can be translated into practice. This project will adopt a prospective design to test the full Social Cognitive Theory (SCT) model for explaining PA in BCS over the course of a 6-month period. Previous research has used individual elements of SCT to understand and predict PA behavior in the general population [11-13], but the full model has yet to be tested, particularly in BCS. The proposed study will include measures to test the full SCT: self-efficacy, goals, outcome expectations, sociocultural factors (facilitators and impediments), and PA behavior [14]. PA has also been shown to positively influence QOL in BCS [7, 8]. However, very little research has been conducted to explain this relationship. Thus, the proposed study will also include measures to test the PA and QOL model proposed by McAuley and colleagues [15] in BCS. This model proposes PA influences global QOL indirectly through its effects on self-efficacy and health related QOL (physical and mental health) whereby self-efficacy is both directly and indirectly related to global QOL through its effect on health related QOL. The public health significance of this study lies in its potential to develop an improved, theoretically sound understanding of PA behavior in BCS as well as a better understanding of the relationship between PA and QOL. These findings could potentially result in better designed, more effective PA programs for BCS which ultimately has the potential to reduce healthcare costs associated with cancer recurrence, comorbidities, and premature death in BCS.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Predoctoral Individual National Research Service Award (F31)
Project #
5F31AG034025-02
Application #
7990388
Study Section
Special Emphasis Panel (ZRG1-F11-B (20))
Program Officer
Stahl, Sidney M
Project Start
2009-09-25
Project End
2011-08-31
Budget Start
2010-09-25
Budget End
2011-08-31
Support Year
2
Fiscal Year
2010
Total Cost
$35,382
Indirect Cost
Name
University of Illinois Urbana-Champaign
Department
Miscellaneous
Type
Other Domestic Higher Education
DUNS #
041544081
City
Champaign
State
IL
Country
United States
Zip Code
61820
Phillips, Siobhan M; Lloyd, Gillian R; Awick, Elizabeth A et al. (2017) Relationship between self-reported and objectively measured physical activity and subjective memory impairment in breast cancer survivors: role of self-efficacy, fatigue and distress. Psychooncology 26:1390-1399
Awick, Elizabeth A; Phillips, Siobhan M; Lloyd, Gillian R et al. (2017) Physical activity, self-efficacy and self-esteem in breast cancer survivors: a panel model. Psychooncology 26:1625-1631
Lloyd, Gillian R; Oza, Sonal; Kozey-Keadle, Sarah et al. (2016) Breast cancer survivors' beliefs and preferences regarding technology-supported sedentary behavior reduction interventions. AIMS Public Health 3:592-614
Phillips, Siobhan M; Lloyd, Gillian R; Awick, Elizabeth A et al. (2016) Correlates of objectively measured sedentary behavior in breast cancer survivors. Cancer Causes Control 27:787-95
Phillips, Siobhan M; Dodd, Kevin W; Steeves, Jeremy et al. (2015) Physical activity and sedentary behavior in breast cancer survivors: New insight into activity patterns and potential intervention targets. Gynecol Oncol 138:398-404
Phillips, Siobhan M; Awick, Elizabeth A; Conroy, David E et al. (2015) Objectively measured physical activity and sedentary behavior and quality of life indicators in survivors of breast cancer. Cancer 121:4044-52
Phillips, Siobhan M; McAuley, Edward (2015) Associations between self-reported post-diagnosis physical activity changes, body weight changes, and psychosocial well-being in breast cancer survivors. Support Care Cancer 23:159-67
Phillips, Siobhan M; McAuley, Edward (2014) Physical activity and quality of life in breast cancer survivors: the role of self-efficacy and health status. Psychooncology 23:27-34
Phillips, Siobhan M; Alfano, Catherine M; Perna, Frank M et al. (2014) Accelerating translation of physical activity and cancer survivorship research into practice: recommendations for a more integrated and collaborative approach. Cancer Epidemiol Biomarkers Prev 23:687-99
Phillips, Siobhan M; McAuley, Edward (2013) Physical activity and fatigue in breast cancer survivors: a panel model examining the role of self-efficacy and depression. Cancer Epidemiol Biomarkers Prev 22:773-81

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