Although a thesis topic has yet to be selected, some areas of interest for the completion of a Ph.D. include: 1) Elucidation of the signaling pathways that lead to lymphocyte activation 2) Understanding of the roles and functions of dendritic cells in antigen presentation, induction of tolerance and immunological memory. 3) Characterization of the human anti-porcine immune response with the goal of aiding the development of xenotransplantation. The selection of these areas of research is based both on my particular interest and on the possible contribution of these studies on the treatment and prevention of disease.
| Shen, Hong; Ackerman, Anne L; Cody, Virginia et al. (2006) Enhanced and prolonged cross-presentation following endosomal escape of exogenous antigens encapsulated in biodegradable nanoparticles. Immunology 117:78-88 |
| Ackerman, Anne L; Kyritsis, Christoph; Tampe, Robert et al. (2003) Early phagosomes in dendritic cells form a cellular compartment sufficient for cross presentation of exogenous antigens. Proc Natl Acad Sci U S A 100:12889-94 |
