Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Predoctoral Individual National Research Service Award (F31)
Project #
8F31DK008865-02
Application #
3024490
Study Section
Special Emphasis Panel (SRC (02))
Project Start
1992-09-24
Project End
Budget Start
1992-09-24
Budget End
1993-09-23
Support Year
2
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of Texas Medical Br Galveston
Department
Type
Schools of Medicine
DUNS #
041367053
City
Galveston
State
TX
Country
United States
Zip Code
77555
Castro, A F; Horton, J K; Vanoye, C G et al. (1999) Mechanism of inhibition of P-glycoprotein-mediated drug transport by protein kinase C blockers. Biochem Pharmacol 58:1723-33
Vanoye, C G; Castro, A F; Pourcher, T et al. (1999) Phosphorylation of P-glycoprotein by PKA and PKC modulates swelling-activated Cl- currents. Am J Physiol 276:C370-8
Vanoye, C G; Altenberg, G A; Reuss, L (1999) Inhibition of P-glycoprotein-mediated transport by a hydrophobic contaminant in commercial gluconate salts. Am J Physiol 276:C1439-42
Vanoye, C G; Altenberg, G A; Reuss, L (1997) P-glycoprotein is not a swelling-activated Cl- channel; possible role as a Cl- channel regulator. J Physiol 502 ( Pt 2):249-58
Han, E S; Vanoye, C G; Altenberg, G A et al. (1996) P-glycoprotein-associated chloride currents revealed by specific block by an anti-P-glycoprotein antibody. Am J Physiol 270:C1370-8
Altenberg, G A; Vanoye, C G; Horton, J K et al. (1994) Unidirectional fluxes of rhodamine 123 in multidrug-resistant cells: evidence against direct drug extrusion from the plasma membrane. Proc Natl Acad Sci U S A 91:4654-7
Altenberg, G A; Deitmer, J W; Glass, D C et al. (1994) P-glycoprotein-associated Cl- currents are activated by cell swelling but do not contribute to cell volume regulation. Cancer Res 54:618-22