My interest is in cardiovascular research. This interest stemmed from the untimely death of my favorite aunt about 10 years ago. She suffered for years from degenerative heart disease and eventually passed away even after a heart transplant. With her death, I became interested in cardiovascular research and have reviewed numerous articles dealing with the cardiovascular system. The Physiology discipline is exciting to me because it would provide me with advanced training in and application to the field of human physiology/cardiovascular research. This program at Cornell University is ideal for me because the research interests and the goals represented under this program make it a unique opportunity for exposure and training.
| Mackins, Christina J; Kano, Seiichiro; Seyedi, Nahid et al. (2006) Cardiac mast cell-derived renin promotes local angiotensin formation, norepinephrine release, and arrhythmias in ischemia/reperfusion. J Clin Invest 116:1063-70 |
| Seyedi, Nahid; Mackins, Christina J; Machida, Takuji et al. (2005) Histamine H3-receptor-induced attenuation of norepinephrine exocytosis: a decreased protein kinase a activity mediates a reduction in intracellular calcium. J Pharmacol Exp Ther 312:272-80 |
| Silver, Randi B; Reid, Alicia C; Mackins, Christina J et al. (2004) Mast cells: a unique source of renin. Proc Natl Acad Sci U S A 101:13607-12 |
| Pergolizzi, Robert G; Ropper, Alexander E; Dragos, Rachel et al. (2003) In vivo trans-splicing of 5' and 3' segments of pre-mRNA directed by corresponding DNA sequences delivered by gene transfer. Mol Ther 8:999-1008 |
