A reasonably large literature has emerged over the past decade suggesting that cortisol activity early in life is socially regulated (Gunnar & Donzella, 2002). Specifically, recent evidence suggests that chronic and/or intense-acute stress during early development can result in long term changes to cortisol activity (Bremmner & Vermetten, 2001); and, an emerging literature now implicates these effects in PTSD and other psychopathology later in life (McEwen, 2000).
The specific aims of this project are: 1) to estimate the relative effects of adverse early experience including child abuse/neglect, intra family conflict and income to needs on the regulation of cortisol response over the course of the morning and in response to intense peer interaction (a novel ecologically relevant stress) in at risk preschool children; 2) to model the moderating effects of childcare/school factors (quality of the care giving environment, quality of the teacher child relationship) and child factors (expressive language, social competence) on associations between risk and the regulation of cortisol response over the course of the morning and in response to intense peer interaction. Participants will consist of sixty 24-36 month old children enrolled in all day childcare. ? ?

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Predoctoral Individual National Research Service Award (F31)
Project #
5F31HD044997-03
Application #
7108683
Study Section
Special Emphasis Panel (ZRG1-BBBP-H (29))
Program Officer
Haverkos, Lynne
Project Start
2004-09-15
Project End
2007-06-07
Budget Start
2006-09-15
Budget End
2007-06-07
Support Year
3
Fiscal Year
2006
Total Cost
$22,287
Indirect Cost
Name
Harvard University
Department
Other Health Professions
Type
Schools of Education
DUNS #
082359691
City
Cambridge
State
MA
Country
United States
Zip Code
02138