Recent evidence suggests that working memory is strongly influenced by negative emotional states and their accompanying cortisol release. This project will examine the influence of positive and negative emotions and cortisol responses on information processing. In a completely within-subjects design, participants will be tested on three days: On a stress day, they will complete a set of mental tasks prior to and following a stressor designed to elicit cortisol release and negative moods; on a positive mood day, the tasks will be performed before and after a film known to produce positive emotions with no cortisol response; on the third day, tasks will be administered before and after a rest period having minimal effects on either moods or cortisol. Tasks will measure working memory and sensory discrimination, two processes thought to be affected differentially by emotions and cortisol secretion. To fully examine the activity of stress hormones during the tasks, cortisol will be measured in repeated saliva samples taken throughout the experimental sessions. Mental task performance will serve as the dependent variable with special attention paid to associations between cortisol levels, reported moods and performance on the tasks. This research may have implications for understanding cognitive alterations accompanying emotional disorders such as depressive illness.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Predoctoral Individual National Research Service Award (F31)
Project #
5F31MH011844-02
Application #
2857993
Study Section
Health Behavior and Prevention Review Committee (HBPR)
Program Officer
Goldschmidts, Walter L
Project Start
1998-12-22
Project End
Budget Start
1998-12-22
Budget End
1999-12-21
Support Year
2
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Oklahoma Health Sciences Center
Department
Psychiatry
Type
Schools of Medicine
DUNS #
937727907
City
Oklahoma City
State
OK
Country
United States
Zip Code
73117
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