This project aims to investigate the status of associative recognition memory in global amnesia in the context of a dual-process model that postulates two separate bases for recognition performance, recollection and familiarity. Four studies will be conducted to examine this issue. The goal of Experiment 1 is to determine whether associative recognition for unrelated word pairs, as compared to single word recognition, is disproportionately impaired in amnesia. Experiment 2 compares associative memory for stimuli in which there is a pre-existing representation of an association (i.e., compound words) to stimuli in which there is not (i.e., unrelated words pairs). Experiment 3 examines whether associative recognition in amnesia is better preserved under the former conditions. Finally, Experiment 4 aims to specify the nature of the familiarity process contributing to amnesics? associative recognition (i.e., conceptual or perceptual) for compound stimuli.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Predoctoral Individual National Research Service Award (F31)
Project #
1F31MH065113-01
Application #
6445037
Study Section
Special Emphasis Panel (ZRG1-BBBP-4 (01))
Program Officer
Goldschmidts, Walter L
Project Start
2001-09-28
Project End
Budget Start
2001-09-28
Budget End
2002-09-27
Support Year
1
Fiscal Year
2001
Total Cost
$36,200
Indirect Cost
Name
Boston University
Department
Psychiatry
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
Giovanello, Kelly Sullivan; Keane, Margaret M; Verfaellie, Mieke (2006) The contribution of familiarity to associative memory in amnesia. Neuropsychologia 44:1859-65
Giovanello, Kelly Sullivan; Verfaellie, Mieke; Keane, Margaret M (2003) Disproportionate deficit in associative recognition relative to item recognition in global amnesia. Cogn Affect Behav Neurosci 3:186-94