18. GOALSFORFELLOWSHIPTRAININGANDCAREER As a clinical psychologist, my goal is to develop a line of research in !the areas of HIV/AIDS, behavioral change, and health-promotion interventions. This fellowship would allow me to broaden and refine both my methodological and clinical skills, and to receive further training in the design, execution, and analysis of high quality research. The Consultation Center at Yale School of Medicine is an ideal setting in which to learn how to conduct community-based research aimed at informing future interventions. With the support of this grant, I would have the unique oppommity of working with a clinical population at high risk for HIV infection, i.e., adults with severe mental illness. I would expand my planned curriculum to include additional courses/seminars in research design, advanced statistical techniques, and HIV/AIDS, In addition, this fellowship would allow me to attend relevant conferences, including the World AIDS Conference, to present my work and to interact with prominent researchers in the field of HIV/AIDS. Most importantly, though, I would be implementing an original, independent research project, thus applying the research and clinical skills I have been acquiring in preparation for a productive, scientific career. SPONSOR 19. NAMEANDDEGREE(S) Kathleen 20. POSITION/RANK Associate 21. RESEARCHINTERESTS/AREAS primary and secondary prevention; J. Sikkema, Ph.D. Professor of Psychiatry Community-level interventions and applications of behavioral medicine to HIV HIV mental health research. RESEARCH PROPOSAL 22. DESCRIPTION _0,o, .... d_v.ceF,ovl.o.) The prevalence of HIV is alarmingly high among adults with severe mental illness (SMI), and a large proportion engages in sexual and substance use behaviors that place them at risk for infection. Unfortunately, the link between psychopathology and HIV risk is poorly understood. While psychiatric symptoms likely have a direct influence on risk behavior, the indirect effects associated with SMI may also play an important role. Unstable relationships and interpersonal violence have frequently been implicated as risk factors for HIV, but this association has not been empirically examined among adults with SMI. The proposed study will address this gap in the literature by exploring the social contextual determinants of HIV risk behavior in this population.
The specific aims are to: (1) examine the effect of psychiatric illness (diagnosis and symptoms) on HIV risk behavior, (2) consider the influence of sexual/physical abuse and (3) examine the role of social networks and relationship quality. Participants will include 100 adults with SMI primarily schizophrenia, schizoaffective disorder, bipolar disorder, and major depression, who live in transitional housing programs in New York, NY and New Haven, CT. Data will be collected through face-to-face interviews using standardized clinical instruments and will be analyzed using structural equation modeling. The information derived from this study will be useful in developing risk-reduction interventions that are sensitive to the specific needs of adults with SMI, including their interpersonal context. PHS 416-1 (Rev. 12/98) Form Page 2 BB cc Individual NRSA Application Table of Contents ========================================Section End===========================================

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Predoctoral Individual National Research Service Award (F31)
Project #
5F31MH067370-03
Application #
6824904
Study Section
Special Emphasis Panel (ZRG1-AARR-7 (01))
Program Officer
Stoff, David M
Project Start
2003-03-20
Project End
2005-11-30
Budget Start
2004-12-01
Budget End
2005-11-30
Support Year
3
Fiscal Year
2005
Total Cost
$39,921
Indirect Cost
Name
Yale University
Department
Psychiatry
Type
Schools of Medicine
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520
Meade, Christina S; Kershaw, Trace S; Hansen, Nathan B et al. (2009) Long-term correlates of childhood abuse among adults with severe mental illness: adult victimization, substance abuse, and HIV sexual risk behavior. AIDS Behav 13:207-16
Meade, Christina S; Sikkema, Kathleen J (2007) Psychiatric and psychosocial correlates of sexual risk behavior among adults with severe mental illness. Community Ment Health J 43:153-69
Meade, Christina S (2006) Sexual risk behavior among persons dually diagnosed with severe mental illness and substance use disorder. J Subst Abuse Treat 30:147-57
Meade, Christina S; Sikkema, Kathleen J (2005) Voluntary HIV testing among adults with severe mental illness: frequency and associated factors. AIDS Behav 9:465-73
Meade, Christina S; Sikkema, Kathleen J (2005) HIV risk behavior among adults with severe mental illness: a systematic review. Clin Psychol Rev 25:433-57