Parasuicidal behavior in adolescence marks significant risk for later suicide and may represent a precursor to the development of borderline personality disorder (BPD). Current theories of parasuicide and BPD suggest that emotion dysregulation underlies the act of self-harm, which serves to regulate overwhelming negative affect. However, no studies have thoroughly explored an emotion dysregulation model of parasuicide, including both cognitive and physiological measures of this trait. The proposed research will compare parasuicidal teens with normal controls and a clinical comparison group with major depressive disorder (n=25/group) on behavioral and physiological measures of emotion regulation. Adolescents and their parent will complete interviews and self-report measures of emotion regulation, psychopathology, substance use and abuse, and histories of parasuicidal behavior. Physiological assessments will be conducted with both the parent and adolescent during baseline, an emotionally evocative film clip from """"""""The Champ,"""""""" and a problem-solving discussion. Physiological indices include electrodermal responding (EDR), respiratory sinus arrhythmia (RSA), and cardiac pre-ejection period (PEP). ? ? ?

National Institute of Health (NIH)
National Institute of Mental Health (NIMH)
Predoctoral Individual National Research Service Award (F31)
Project #
Application #
Study Section
Special Emphasis Panel (ZRG1-F12B-L (20))
Program Officer
Ferrell, Courtney
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Washington
Schools of Arts and Sciences
United States
Zip Code
Crowell, Sheila E; Butner, Jonathan E; Wiltshire, Travis J et al. (2017) Evaluating Emotional and Biological Sensitivity to Maternal Behavior among Self-injuring and Depressed Adolescent Girls Using Nonlinear Dynamics. Clin Psychol Sci 5:272-285
Beauchaine, Theodore P; Crowell, Sheila E; Hsiao, Ray C (2015) Post-dexamethasone cortisol, self-inflicted injury, and suicidal ideation among depressed adolescent girls. J Abnorm Child Psychol 43:619-32
Crowell, Sheila E; Baucom, Brian R; Yaptangco, Mona et al. (2014) Emotion dysregulation and dyadic conflict in depressed and typical adolescents: evaluating concordance across psychophysiological and observational measures. Biol Psychol 98:50-8
Crowell, Sheila E; Baucom, Brian R; McCauley, Elizabeth et al. (2013) Mechanisms of contextual risk for adolescent self-injury: invalidation and conflict escalation in mother-child interactions. J Clin Child Adolesc Psychol 42:467-80
Beauchaine, Theodore P; Gatzke-Kopp, Lisa M (2012) Instantiating the multiple levels of analysis perspective in a program of study on externalizing behavior. Dev Psychopathol 24:1003-18
Crowell, Sheila E; Beauchaine, Theodore P; Hsiao, Ray C et al. (2012) Differentiating adolescent self-injury from adolescent depression: possible implications for borderline personality development. J Abnorm Child Psychol 40:45-57
Hughes, Amy E; Crowell, Sheila E; Uyeji, Lauren et al. (2012) A developmental neuroscience of borderline pathology: emotion dysregulation and social baseline theory. J Abnorm Child Psychol 40:21-33
Vander Stoep, Ann; Adrian, Molly; McCauley, Elizabeth et al. (2011) Risk for suicidal ideation and suicide attempts associated with co-occurring depression and conduct problems in early adolescence. Suicide Life Threat Behav 41:316-29
Beauchaine, Theodore P; Klein, Daniel N; Crowell, Sheila E et al. (2009) Multifinality in the development of personality disorders: a Biology x Sex x Environment interaction model of antisocial and borderline traits. Dev Psychopathol 21:735-70
Vasilev, Christina A; Crowell, Sheila E; Beauchaine, Theodore P et al. (2009) Correspondence between physiological and self-report measures of emotion dysregulation: a longitudinal investigation of youth with and without psychopathology. J Child Psychol Psychiatry 50:1357-64

Showing the most recent 10 out of 13 publications