Abstract

Overall purposes of the proposed secondary data analysis (SDA) are to use social cognitive theory: 1) to assess the effectiveness of a cognitive behavioral antiretroviral (ART) adherence intervention in persons with past or current substance use, and 2) to understand the psychological variables affecting ART adherence behavior in persons with HIV/AIDS and past or current substance use. Primary aims are: 1) to compare the baseline ART adherence of HIV-infected persons who are and are not substance users, and 2) to compare the effect of the parent study's cognitive-behavioral ART adherence intervention with usual care on the ART adherence of HIV-infected persons who are substance users. The secondary aim is to explore if self-efficacy mediates the effects of social support, depression, and personality characteristics on the ART adherence of HIV-infected substance users. Multiple linear regression, repeated measures analysis, and path analysis will be used to evaluate each of the aims, respectively. Findings will be applicable to the design of specialized ART adherence interventions for this vulnerable population, thus leading to decreased HIV-related morbidity and delayed mortality, lower healthcare costs, and a reduced public health risk of resistant strains of HIV. ? ?

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Nursing Research (NINR)
Type
Predoctoral Individual National Research Service Award (F31)
Project #
5F31NR008822-03
Application #
7008166
Study Section
National Institute of Nursing Research Initial Review Group (NRRC)
Program Officer
Hare, Martha L
Project Start
2004-01-01
Project End
2008-08-31
Budget Start
2006-01-01
Budget End
2006-12-31
Support Year
3
Fiscal Year
2006
Total Cost
$43,572
Indirect Cost

  Institution

Name
University of Pittsburgh
Department
Miscellaneous
Type
Schools of Nursing
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213

  Publications

Broyles, Lauren Matukaitis; Gordon, Adam J; Sereika, Susan M et al. (2011) Do words matter? Incongruent responses to inconsistently worded AUDIT-C alcohol screening instruments. Subst Abus 32:202-9
Broyles, Lauren Matukaitis; Gordon, Adam J; Sereika, Susan M et al. (2011) Predictive Utility of Brief Alcohol Use Disorders Identification Test (AUDIT) for human immunodeficiency virus antiretroviral medication nonadherence. Subst Abus 32:252-61
Broyles, Lauren M; Colbert, Alison M; Tate, Judith A et al. (2008) Clinicians'evaluation and management of mental health, substance abuse, and chronic pain conditions in the intensive care unit. Crit Care Med 36:87-93
Broyles, Lauren M; Colbert, Alison M; Erlen, Judith A (2005) Medication practice and feminist thought: a theoretical and ethical response to adherence in HIV/AIDS. Bioethics 19:362-78