A novel death pathway in cerebellar Purkinje neurons

McClure, Maria L.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Neurological Disorders and Stroke (NINDS)
• Type: Predoctoral Individual National Research Service Award (F31)
• Project #: 5F31NS045560-02
• Application #: 6710643
• Study Section: Special Emphasis Panel (ZRG1-F05 (29))
• Program Officer: Mamounas, Laura
• Project Start: 2002-11-29
• Project End: 2004-09-29
• Budget Start: 2003-11-29
• Budget End: 2004-09-29
• Support Year: 2
• Fiscal Year: 2004
• Total Cost: $20,060

Institution

• Name: University of Colorado Denver
• Department: Pharmacology
• Type: Schools of Medicine
• DUNS #: 041096314
• City: Aurora
• State: CO
• Country: United States
• Zip Code: 80045

Publications

Bains, Mona; Zaegel, Vincent; Mize-Berge, Janna et al. (2011) IGF-I stimulates Rab7-RILP interaction during neuronal autophagy. Neurosci Lett 488:112-7

Bains, Mona; Florez-McClure, Maria L; Heidenreich, Kim A (2009) Insulin-like growth factor-I prevents the accumulation of autophagic vesicles and cell death in Purkinje neurons by increasing the rate of autophagosome-to-lysosome fusion and degradation. J Biol Chem 284:20398-407