Mutagenic Analysis of the Papillomavirus E5 Oncoprotein

Sparkowski, Jason J.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Postdoctoral Individual National Research Service Award (F32)
• Project #: 5F32AI008823-02
• Application #: 2058806
• Study Section: Immunology, Virology, and Pathology Study Section (IVP)
• Project Start: 1994-09-15
• Budget Start: 1994-09-15
• Budget End: 1995-09-14
• Support Year: 2
• Fiscal Year: 1994

Institution

• Name: Georgetown University
• Department: Pathology
• Type: Schools of Dentistry
• DUNS #: 049515844
• City: Washington
• State: DC
• Country: United States
• Zip Code: 20057

Publications

Sparkowski, J; Mense, M; Anders, J et al. (1996) E5 oncoprotein transmembrane mutants dissociate fibroblast transforming activity from 16-kilodalton protein binding and platelet-derived growth factor receptor binding and phosphorylation. J Virol 70:2420-30

Sparkowski, J; Anders, J; Schlegel, R (1995) E5 oncoprotein retained in the endoplasmic reticulum/cis Golgi still induces PDGF receptor autophosphorylation but does not transform cells. EMBO J 14:3055-63

Sparkowski, J; Anders, J; Schlegel, R (1994) Mutation of the bovine papillomavirus E5 oncoprotein at amino acid 17 generates both high- and low-transforming variants. J Virol 68:6120-3