Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Postdoctoral Individual National Research Service Award (F32)
Project #
5F32AR008080-02
Application #
3031892
Study Section
Clinical Sciences Study Section (CLN)
Project Start
1990-08-23
Project End
Budget Start
1990-08-23
Budget End
1991-08-22
Support Year
2
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Abbott Laboratories
Department
Type
DUNS #
City
North Chicago
State
IL
Country
United States
Zip Code
60064
Pollock, J S; Nakane, M; Buttery, L D et al. (1993) Characterization and localization of endothelial nitric oxide synthase using specific monoclonal antibodies. Am J Physiol 265:C1379-87
Pollock, J S; Forstermann, U; Mitchell, J A et al. (1991) Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells. Proc Natl Acad Sci U S A 88:10480-4
Mitchell, J A; Forstermann, U; Warner, T D et al. (1991) Endothelial cells have a particulate enzyme system responsible for EDRF formation: measurement by vascular relaxation. Biochem Biophys Res Commun 176:1417-23
Forstermann, U; Schmidt, H H; Pollock, J S et al. (1991) Isoforms of nitric oxide synthase. Characterization and purification from different cell types. Biochem Pharmacol 42:1849-57
Schmidt, H H; Pollock, J S; Nakane, M et al. (1991) Purification of a soluble isoform of guanylyl cyclase-activating-factor synthase. Proc Natl Acad Sci U S A 88:365-9
Forstermann, U; Pollock, J S; Schmidt, H H et al. (1991) Calmodulin-dependent endothelium-derived relaxing factor/nitric oxide synthase activity is present in the particulate and cytosolic fractions of bovine aortic endothelial cells. Proc Natl Acad Sci U S A 88:1788-92
Forstermann, U; Gorsky, L D; Pollock, J S et al. (1990) Hormone-induced biosynthesis of endothelium-derived relaxing factor/nitric oxide-like material in N1E-115 neuroblastoma cells requires calcium and calmodulin. Mol Pharmacol 38:7-13