Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Postdoctoral Individual National Research Service Award (F32)
Project #
1F32CA008316-01
Application #
3033434
Study Section
(BI)
Project Start
1988-02-11
Project End
Budget Start
1987-09-01
Budget End
1988-08-31
Support Year
1
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of Virginia
Department
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Bouton, A H; Kanner, S B; Vines, R R et al. (1991) Transformation by pp60src or stimulation of cells with epidermal growth factor induces the stable association of tyrosine-phosphorylated cellular proteins with GTPase-activating protein. Mol Cell Biol 11:945-53
Bouton, A H; Kanner, S B; Vines, R R et al. (1991) Tyrosine phosphorylation of three cellular proteins correlates with transformation of rat 1 cells by pp60src. Mol Carcinog 4:145-52
Kanner, S B; Reynolds, A B; Wang, H C et al. (1991) The SH2 and SH3 domains of pp60src direct stable association with tyrosine phosphorylated proteins p130 and p110. EMBO J 10:1689-98
Wu, H; Reynolds, A B; Kanner, S B et al. (1991) Identification and characterization of a novel cytoskeleton-associated pp60src substrate. Mol Cell Biol 11:5113-24
Kanner, S B; Reynolds, A B; Parsons, J T (1991) Tyrosine phosphorylation of a 120-kilodalton pp60src substrate upon epidermal growth factor and platelet-derived growth factor receptor stimulation and in polyomavirus middle-T-antigen-transformed cells. Mol Cell Biol 11:713-20
Kanner, S B; Reynolds, A B; Vines, R R et al. (1990) Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases. Proc Natl Acad Sci U S A 87:3328-32
Reynolds, A B; Kanner, S B; Wang, H C et al. (1989) Stable association of activated pp60src with two tyrosine-phosphorylated cellular proteins. Mol Cell Biol 9:3951-8
Kanner, S B; Gilmer, T M; Reynolds, A B et al. (1989) Novel tyrosine phosphorylations accompany the activation of pp60c-src during chemical carcinogenesis. Oncogene 4:295-300
Kanner, S B; Reynolds, A B; Parsons, J T (1989) Immunoaffinity purification of tyrosine-phosphorylated cellular proteins. J Immunol Methods 120:115-24
Kanner, S B; Parsons, S J; Parsons, J T et al. (1988) Activation of pp60c-src tyrosine kinase specific activity in tumor-derived Syrian hamster embryo cells. Oncogene 2:327-35