Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Postdoctoral Individual National Research Service Award (F32)
Project #
3F32DK008206-03S1
Application #
3036888
Study Section
Clinical Sciences Study Section (CLN)
Project Start
1991-10-01
Project End
Budget Start
1991-10-01
Budget End
1992-09-30
Support Year
3
Fiscal Year
1991
Total Cost
Indirect Cost
Name
University of Tennessee Health Science Center
Department
Type
Schools of Medicine
DUNS #
941884009
City
Memphis
State
TN
Country
United States
Zip Code
38163
McKnight, G L; Mudri, S L; Mathewes, S L et al. (1992) Molecular cloning, cDNA sequence, and bacterial expression of human glutamine:fructose-6-phosphate amidotransferase. J Biol Chem 267:25208-12
Traxinger, R R; Marshall, S (1992) Insulin regulation of pyruvate kinase activity in isolated adipocytes. Crucial role of glucose and the hexosamine biosynthesis pathway in the expression of insulin action. J Biol Chem 267:9718-23
Marshall, S; Bacote, V; Traxinger, R R (1991) Complete inhibition of glucose-induced desensitization of the glucose transport system by inhibitors of mRNA synthesis. Evidence for rapid turnover of glutamine:fructose-6-phosphate amidotransferase. J Biol Chem 266:10155-61
Traxinger, R R; Marshall, S (1991) Coordinated regulation of glutamine:fructose-6-phosphate amidotransferase activity by insulin, glucose, and glutamine. Role of hexosamine biosynthesis in enzyme regulation. J Biol Chem 266:10148-54
Marshall, S; Bacote, V; Traxinger, R R (1991) Discovery of a metabolic pathway mediating glucose-induced desensitization of the glucose transport system. Role of hexosamine biosynthesis in the induction of insulin resistance. J Biol Chem 266:4706-12
Traxinger, R R; Marshall, S (1990) Glucose regulation of insulin receptor affinity in primary cultured adipocytes. J Biol Chem 265:18879-83
Traxinger, R R; Marshall, S (1990) Suitability of 2-deoxyglucose for measuring initial rates of glucose uptake in isolated adipocytes. Biochem Int 22:607-15
Traxinger, R R; Marshall, S (1989) Role of amino acids in modulating glucose-induced desensitization of the glucose transport system. J Biol Chem 264:20910-6