Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Postdoctoral Individual National Research Service Award (F32)
Project #
7F32DK009231-02
Application #
2136280
Study Section
Special Emphasis Panel (ZRG2-PSF (01))
Program Officer
Hyde, James F
Project Start
1996-08-02
Project End
Budget Start
1996-08-02
Budget End
1997-08-01
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Oregon Health and Science University
Department
Type
Organized Research Units
DUNS #
009584210
City
Portland
State
OR
Country
United States
Zip Code
97239
Haskell-Luevano, C; Rosenquist, A; Souers, A et al. (1999) Compounds that activate the mouse melanocortin-1 receptor identified by screening a small molecule library based upon the beta-turn. J Med Chem 42:4380-7
Chen, P; Li, C; Haskell-Luevano, C et al. (1999) Altered expression of agouti-related protein and its colocalization with neuropeptide Y in the arcuate nucleus of the hypothalamus during lactation. Endocrinology 140:2645-50
Hadley, M E; Haskell-Luevano, C (1999) The proopiomelanocortin system. Ann N Y Acad Sci 885:1-21
Haskell-Luevano, C; Nikiforovich, G; Sharma, S D et al. (1997) Biological and conformational examination of stereochemical modifications using the template melanotropin peptide, Ac-Nle-c[Asp-His-Phe-Arg-Trp-Ala-Lys]-NH2, on human melanocortin receptors. J Med Chem 40:1738-48
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Haskell-Luevano, C; Toth, K; Boteju, L et al. (1997) beta-Methylation of the Phe7 and Trp9 melanotropin side chain pharmacophores affects ligand-receptor interactions and prolonged biological activity. J Med Chem 40:2740-9
Haskell-Luevano, C; Hendrata, S; North, C et al. (1997) Discovery of prototype peptidomimetic agonists at the human melanocortin receptors MC1R and MC4R. J Med Chem 40:2133-9
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Haskell-Luevano, C; Sawyer, T K; Hendrata, S et al. (1996) Truncation studies of alpha-melanotropin peptides identify tripeptide analogues exhibiting prolonged agonist bioactivity. Peptides 17:995-1002
Hadley, M E; Hruby, V J; Jiang, J et al. (1996) Melanocortin receptors: identification and characterization by melanotropic peptide agonists and antagonists. Pigment Cell Res 9:213-34