Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Postdoctoral Individual National Research Service Award (F32)
Project #
1F32DK009436-01
Application #
2136533
Study Section
General Medicine B Study Section (GMB)
Program Officer
Hyde, James F
Project Start
1996-09-10
Project End
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115
Murphey, E D; Chattopadhyay, N; Bai, M et al. (2000) Up-regulation of the parathyroid calcium-sensing receptor after burn injury in sheep: a potential contributory factor to postburn hypocalcemia. Crit Care Med 28:3885-90
Bai, M (1999) Structure and function of the extracellular calcium-sensing receptor (Review). Int J Mol Med 4:115-25
Bai, M; Trivedi, S; Kifor, O et al. (1999) Intermolecular interactions between dimeric calcium-sensing receptor monomers are important for its normal function. Proc Natl Acad Sci U S A 96:2834-9
Watanabe, T; Bai, M; Lane, C R et al. (1998) Familial hypoparathyroidism: identification of a novel gain of function mutation in transmembrane domain 5 of the calcium-sensing receptor. J Clin Endocrinol Metab 83:2497-502
Bai, M; Trivedi, S; Brown, E M (1998) Dimerization of the extracellular calcium-sensing receptor (CaR) on the cell surface of CaR-transfected HEK293 cells. J Biol Chem 273:23605-10
Bai, M; Trivedi, S; Lane, C R et al. (1998) Protein kinase C phosphorylation of threonine at position 888 in Ca2+o-sensing receptor (CaR) inhibits coupling to Ca2+ store release. J Biol Chem 273:21267-75
Bai, M; Janicic, N; Trivedi, S et al. (1997) Markedly reduced activity of mutant calcium-sensing receptor with an inserted Alu element from a kindred with familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. J Clin Invest 99:1917-25
Bai, M; Quinn, S; Trivedi, S et al. (1996) Expression and characterization of inactivating and activating mutations in the human Ca2+o-sensing receptor. J Biol Chem 271:19537-45