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Harman, A W; Kyle, M E; Serroni, A et al. (1991) The killing of cultured hepatocytes by N-acetyl-p-benzoquinone imine (NAPQI) as a model of the cytotoxicity of acetaminophen. Biochem Pharmacol 41:1111-7
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Farber, J L; Kyle, M E; Coleman, J B (1990) Mechanisms of cell injury by activated oxygen species. Lab Invest 62:670-9
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Kyle, M E; Nakae, D; Sakaida, S et al. (1989) Protein thiol depletion and the killing of cultured hepatocytes by hydrogen peroxide. Biochem Pharmacol 38:3797-805
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Masaki, N; Kyle, M E; Farber, J L (1989) tert-butyl hydroperoxide kills cultured hepatocytes by peroxidizing membrane lipids. Arch Biochem Biophys 269:390-9
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Masaki, N; Kyle, M E; Serroni, A et al. (1989) Mitochondrial damage as a mechanism of cell injury in the killing of cultured hepatocytes by tert-butyl hydroperoxide. Arch Biochem Biophys 270:672-80
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Farber, J L; Leonard, T B; Kyle, M E et al. (1988) Peroxidation-dependent and peroxidation-independent mechanisms by which acetaminophen kills cultured rat hepatocytes. Arch Biochem Biophys 267:640-50
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Miccadei, S; Nakae, D; Kyle, M E et al. (1988) Oxidative cell injury in the killing of cultured hepatocytes by allyl alcohol. Arch Biochem Biophys 265:302-10
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Kyle, M E; Nakae, D; Sakaida, I et al. (1988) Endocytosis of superoxide dismutase is required in order for the enzyme to protect hepatocytes from the cytotoxicity of hydrogen peroxide. J Biol Chem 263:3784-9
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Kyle, M E; Nakae, D; Serroni, A et al. (1988) 1,3-(2-Chloroethyl)-1-nitrosourea potentiates the toxicity of acetaminophen both in the phenobarbital-induced rat and in hepatocytes cultured from such animals. Mol Pharmacol 34:584-9
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Miccadei, S; Kyle, M E; Gilfor, D et al. (1988) Toxic consequence of the abrupt depletion of glutathione in cultured rat hepatocytes. Arch Biochem Biophys 265:311-20
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