Project Start
1989-02-01
Project End
Budget Start
1989-02-01
Budget End
1990-01-31
Support Year
2
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Karolinska Institute
Department
Type
DUNS #
350582235
City
Stockholm
State
Country
Sweden
Zip Code
171 77
Llopis, J; Farrell, G C; Duddy, S K et al. (1993) Eicosanoids released following inhibition of the endoplasmic reticulum Ca2+ pump stimulate Ca2+ efflux in the perfused rat liver. Biochem Pharmacol 45:2209-14
Llopis, J; Kass, G E; Duddy, S K et al. (1991) Mobilization of the hormone-sensitive calcium pool increases hepatocyte tight junctional permeability in the perfused rat liver. FEBS Lett 280:84-6
Moore, G A; Kass, G E; Duddy, S K et al. (1990) 2,5-Di(tert-butyl)-1,4-benzohydroquinone--a novel mobilizer of the inositol 1,4,5-trisphosphate-sensitive Ca2+ pool. Free Radic Res Commun 8:337-45
Kass, G E; Llopis, J; Chow, S C et al. (1990) Receptor-operated calcium influx in rat hepatocytes. Identification and characterization using manganese. J Biol Chem 265:17486-92
Farrell, G C; Duddy, S K; Kass, G E et al. (1990) Release of Ca2+ from the endoplasmic reticulum is not the mechanism for bile acid-induced cholestasis and hepatotoxicity in the intact rat liver. J Clin Invest 85:1255-9
Kass, G E; Duddy, S K; Moore, G A et al. (1989) 2,5-Di-(tert-butyl)-1,4-benzohydroquinone rapidly elevates cytosolic Ca2+ concentration by mobilizing the inositol 1,4,5-trisphosphate-sensitive Ca2+ pool. J Biol Chem 264:15192-8
Kass, G E; Duddy, S K; Orrenius, S (1989) Activation of hepatocyte protein kinase C by redox-cycling quinones. Biochem J 260:499-507
Warngard, L; Hemming, H; Flodstrom, S et al. (1989) Mechanistic studies on the DDT-induced inhibition of intercellular communication. Carcinogenesis 10:471-6
Duddy, S K; Kass, G E; Orrenius, S (1989) Ca2(+)-mobilizing hormones stimulate Ca2+ efflux from hepatocytes. J Biol Chem 264:20863-6
Cotgreave, I A; Duddy, S K; Kass, G E et al. (1989) Studies on the anti-inflammatory activity of ebselen. Ebselen interferes with granulocyte oxidative burst by dual inhibition of NADPH oxidase and protein kinase C? Biochem Pharmacol 38:649-56