The main objective of this research is to evaluate exposures associated with allergy, asthma and lung function among nurses. The research will involve analysis of data from the European Community Respiratory Health Survey (ECRHS), a follow-up study of a general population sample of approximately 7000 young adults in Europe, Australia and the US. The first specific aim is to evaluate workplace exposure to respiratory irritants and sensitizers among professional nurses employed in a range of industries and medical settings, including hospitals, clinics, and private health care offices. The second specific aim is to assess whether such exposures contribute to the incidence of respiratory symptoms and lung function decline. Analyses will examine the frequency and severity of new onset asthma and allergy symptoms, exacerbation of symptoms in previously symptomatic individuals, sensitization of previously asymptomatic individuals, and behavioral consequences of the frequent and/or severe symptoms. In addition, this research will also engage the postdoctoral fellow in other asthma studies within the ECRHS, including assessing potential occupational exposures in other non industrial workplaces, such as office buildings and schools, and assessing gene-environment interactions. ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Postdoctoral Individual National Research Service Award (F32)
Project #
1F32ES014142-01X1
Application #
7123218
Study Section
Epidemiology of Clinical Disorders and Aging Study Section (ECDA)
Program Officer
Humble, Michael C
Project Start
2006-01-20
Project End
2009-01-19
Budget Start
2006-01-20
Budget End
2007-01-19
Support Year
1
Fiscal Year
2005
Total Cost
$6,500
Indirect Cost
Name
Fundacio Imim
Department
Type
DUNS #
465821168
City
Barcelona
State
Country
Spain
Zip Code
08003
Mirabelli, Maria C; Vizcaya, David; Marti Margarit, Anna et al. (2012) Occupational risk factors for hand dermatitis among professional cleaners in Spain. Contact Dermatitis 66:188-96
Olivieri, M; Mirabelli, M C; Plana, E et al. (2010) Healthy hire effect, job selection and inhalation exposure among young adults with asthma. Eur Respir J 36:517-23
Mirabelli, Maria C; Zock, Jan-Paul; D'Errico, Angelo et al. (2009) Occupational exposure to high molecular weight allergens and lymphoma risk among Italian adults. Cancer Epidemiol Biomarkers Prev 18:2650-4
Mirabelli, Maria C; Künzli, Nino; Avol, Edward et al. (2009) Respiratory symptoms following wildfire smoke exposure: airway size as a susceptibility factor. Epidemiology 20:451-9
Mirabelli, Maria C; Olivieri, Mario; Kromhout, Hans et al. (2009) Inhalation incidents and respiratory health: results from the European Community Respiratory Health Survey. Am J Ind Med 52:17-24
Mirabelli, Maria C; Zock, Jan-Paul; Bircher, Andreas J et al. (2009) Metalworking exposures and persistent skin symptoms in the ECRHS II and SAPALDIA 2 cohorts. Contact Dermatitis 60:256-63
Radon, K; Gerhardinger, U; Schulze, A et al. (2008) Occupation and adult onset of rhinitis in the general population. Occup Environ Med 65:38-43
Mirabelli, Maria C; Zock, Jan-Paul; Plana, Estel et al. (2007) Occupational risk factors for asthma among nurses and related healthcare professionals in an international study. Occup Environ Med 64:474-9
Mirabelli, Maria C; Zock, Jan-Paul; Plana, Estel et al. (2007) Employment status and use of respiratory protection among metalworkers, solderers and welders. Occup Environ Med 64:548-52