We will test the hypothesis that the visual system matches features between the left- and right-eye images using cooperative processing among neurons in primary visual cortex that respond specifically to horizontal disparities between these images. Effective connections between neurons are quantified using cross-correlation between spike trains. We will examine the dynamics of these effective connections during changes in depth rendered in dynamic random dot stereograms and compare them to predictions made by cooperative algorithms. In addition, we will test the hypothesis that cooperative mechanisms also facilitate detecting orientation (in depth) of a surface. We will extend our approach by measuring the dynamics of effective connections while displaying dynamic random dot stereogram gradients. Surface orientation is an elementary step in detecting more complex depth-based patterns of surfaces. The results of the proposed project will provide fundamental details about the underlying mechanisms of neural integration. Understanding how early disparity signals are integrated will allow us to understand how complex depth perception evolves through the visual system. A general motivation of this project is to understand how neurons interact, which is fundamental to determining how the brain functions. More specifically, figuring out how the visual system computes depth from two-dimensional images will be essential in developing treatment for neuropathology with known depth perception deficiencies.
| Samonds, Jason M; Potetz, Brian R; Lee, Tai Sing (2014) Sample skewness as a statistical measurement of neuronal tuning sharpness. Neural Comput 26:860-906 |
| Samonds, Jason M; Potetz, Brian R; Tyler, Christopher W et al. (2013) Recurrent connectivity can account for the dynamics of disparity processing in V1. J Neurosci 33:2934-46 |
| Samonds, Jason M; Potetz, Brian R; Lee, Tai Sing (2012) Relative luminance and binocular disparity preferences are correlated in macaque primary visual cortex, matching natural scene statistics. Proc Natl Acad Sci U S A 109:6313-8 |
| Samonds, Jason M; Potetz, Brian R; Lee, Tai Sing (2009) Cooperative and competitive interactions facilitate stereo computations in macaque primary visual cortex. J Neurosci 29:15780-95 |
