Silyl Steroid Inactivation of P450scc

Hedstrom, Lizbeth K.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of General Medical Sciences (NIGMS)
• Type: Postdoctoral Individual National Research Service Award (F32)
• Project #: 1F32GM010504-01
• Application #: 3040496
• Study Section: (BI)
• Project Start: 1986-01-14
• Budget Start: 1985-09-01
• Budget End: 1986-08-31
• Support Year: 1
• Fiscal Year: 1985

Institution

• Name: Massachusetts Institute of Technology
• Type: Schools of Arts and Sciences
• City: Cambridge
• State: MA
• Country: United States

Publications

Hedstrom, L; Wang, C C (1990) Mycophenolic acid and thiazole adenine dinucleotide inhibition of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: implications on enzyme mechanism. Biochemistry 29:849-54

Hedstrom, L; Cheung, K S; Wang, C C (1990) A novel mechanism of mycophenolic acid resistance in the protozoan parasite Tritrichomonas foetus. Biochem Pharmacol 39:151-60

Hedstrom, L; Wang, C C (1989) Purine base transport in wild-type and mycophenolic acid-resistant Tritrichomonas foetus. Mol Biochem Parasitol 35:219-27

Verham, R; Meek, T D; Hedstrom, L et al. (1987) Purification, characterization, and kinetic analysis of inosine 5'-monophosphate dehydrogenase of Tritrichomonas foetus. Mol Biochem Parasitol 24:1-12