Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Postdoctoral Individual National Research Service Award (F32)
Project #
5F32GM010766-02
Application #
3040873
Study Section
Behavioral and Neurosciences Study Section (BNS)
Project Start
1986-12-29
Project End
Budget Start
1986-12-29
Budget End
1987-12-28
Support Year
2
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Abramson, S N; Trischman, J A; Tapiolas, D M et al. (1991) Structure/activity and molecular modeling studies of the lophotoxin family of irreversible nicotinic receptor antagonists. J Med Chem 34:1798-804
Luetje, C W; Wada, K; Rogers, S et al. (1990) Neurotoxins distinguish between different neuronal nicotinic acetylcholine receptor subunit combinations. J Neurochem 55:632-40
Abramson, S N; Ellisman, M H; Deerinck, T J et al. (1989) Differences in structure and distribution of the molecular forms of acetylcholinesterase. J Cell Biol 108:2301-11
Abramson, S N; Radic, Z; Manker, D et al. (1989) Onchidal: a naturally occurring irreversible inhibitor of acetylcholinesterase with a novel mechanism of action. Mol Pharmacol 36:349-54
Abramson, S N; Li, Y; Culver, P et al. (1989) An analog of lophotoxin reacts covalently with Tyr190 in the alpha-subunit of the nicotinic acetylcholine receptor. J Biol Chem 264:12666-72
Abramson, S N; Culver, P; Kline, T et al. (1988) Lophotoxin and related coral toxins covalently label the alpha-subunit of the nicotinic acetylcholine receptor. J Biol Chem 263:18568-73