Sequence Dependence of DNA Polymerase Fidelity

Bloom, Linda B.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of General Medical Sciences (NIGMS)
• Type: Postdoctoral Individual National Research Service Award (F32)
• Project #: 5F32GM015034-02
• Application #: 2169602
• Study Section: Biomedical Sciences Study Section (BIOM)
• Project Start: 1993-01-01
• Budget Start: 1993-01-01
• Budget End: 1993-12-31
• Support Year: 2
• Fiscal Year: 1993

Institution

• Name: University of Southern California
• Department: Biology
• Type: Schools of Arts and Sciences
• DUNS #: 041544081
• City: Los Angeles
• State: CA
• Country: United States
• Zip Code: 90089

Publications

Bloom, L B; Otto, M R; Eritja, R et al. (1994) Pre-steady-state kinetic analysis of sequence-dependent nucleotide excision by the 3'-exonuclease activity of bacteriophage T4 DNA polymerase. Biochemistry 33:7576-86

Yu, H; Eritja, R; Bloom, L B et al. (1993) Ionization of bromouracil and fluorouracil stimulates base mispairing frequencies with guanine. J Biol Chem 268:15935-43

Bloom, L B; Otto, M R; Beechem, J M et al. (1993) Influence of 5'-nearest neighbors on the insertion kinetics of the fluorescent nucleotide analog 2-aminopurine by Klenow fragment. Biochemistry 32:11247-58