Mutagenesis of Phospholipase A2

Annand, Robert R.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of General Medical Sciences (NIGMS)
• Type: Postdoctoral Individual National Research Service Award (F32)
• Project #: 5F32GM015464-03
• Application #: 2169946
• Study Section: Biomedical Sciences Study Section (BIOM)
• Project Start: 1994-08-01
• Budget Start: 1994-08-01
• Budget End: 1995-07-31
• Support Year: 3
• Fiscal Year: 1994

Institution

• Name: University of Washington
• Department: Chemistry
• Type: Schools of Arts and Sciences
• DUNS #: 135646524
• City: Seattle
• State: WA
• Country: United States
• Zip Code: 98195

Publications

Ghomashchi, F; Lin, Y; Hixon, M S et al. (1998) Interfacial recognition by bee venom phospholipase A2: insights into nonelectrostatic molecular determinants by charge reversal mutagenesis. Biochemistry 37:6697-710

Dudler, T; Machado, D C; Kolbe, L et al. (1995) A link between catalytic activity, IgE-independent mast cell activation, and allergenicity of bee venom phospholipase A2. J Immunol 155:2605-13

Dudler, T; Schneider, T; Annand, R R et al. (1994) Antigenic surface of the bee venom allergen phospholipase A2. Structural functional analysis of human IgG4 antibodies reveals potential role in protection. J Immunol 152:5514-22