Identifying Constraints on Intron Evolution

Muse, Spencer V.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of General Medical Sciences (NIGMS)
• Type: Postdoctoral Individual National Research Service Award (F32)
• Project #: 5F32GM016250-02
• Application #: 2170693
• Study Section: Mammalian Genetics Study Section (MGN)
• Project Start: 1994-09-01
• Budget Start: 1994-09-01
• Budget End: 1995-08-31
• Support Year: 2
• Fiscal Year: 1994

Institution

• Name: Pennsylvania State University
• Department: Biology
• Type: Schools of Arts and Sciences
• City: University Park
• State: PA
• Country: United States
• Zip Code: 16802

Publications

Muse, S V (1996) Estimating synonymous and nonsynonymous substitution rates. Mol Biol Evol 13:105-14

Clark, A G; Leicht, B G; Muse, S V (1996) Length variation and secondary structure of introns in the Mlc1 gene in six species of Drosophila. Mol Biol Evol 13:471-82

Muse, S V (1995) Evolutionary analyses of DNA sequences subject to constraints of secondary structure. Genetics 139:1429-39

Leicht, B G; Muse, S V; Hanczyc, M et al. (1995) Constraints on intron evolution in the gene encoding the myosin alkali light chain in Drosophila. Genetics 139:299-308

Kirby, D A; Muse, S V; Stephan, W (1995) Maintenance of pre-mRNA secondary structure by epistatic selection. Proc Natl Acad Sci U S A 92:9047-51

Muse, S V; Gaut, B S (1994) A likelihood approach for comparing synonymous and nonsynonymous nucleotide substitution rates, with application to the chloroplast genome. Mol Biol Evol 11:715-24