The long-term goal of my postdoctoral research is to understand mutation-induced adaptation in biological systems. Specifically, I wish to determine correlations between optimal mutation rates and environmental stresses, and to elucidate general power laws that govern dynamics in the gene sequence space. I will also develop mathematical models for specific biological networks, to quantitatively predict the mutation-induced evolution of these networks when subject to various environmental stresses. This study will require the use of genomic and proteomic databases, as well as predictive methods from computational biology, in order to determine the function of the various evolving components of the biological networks under study. ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Postdoctoral Individual National Research Service Award (F32)
Project #
5F32GM067474-02
Application #
6723685
Study Section
Special Emphasis Panel (ZRG1-F08 (20))
Program Officer
Wolfe, Paul B
Project Start
2003-03-03
Project End
2006-03-02
Budget Start
2004-03-03
Budget End
2005-03-02
Support Year
2
Fiscal Year
2004
Total Cost
$42,976
Indirect Cost
Name
Harvard University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
082359691
City
Cambridge
State
MA
Country
United States
Zip Code
02138