Molecular Modeling of Inhibitor-Protease Complexes

Plaskon, Richard R.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Postdoctoral Individual National Research Service Award (F32)
• Project #: 5F32HL007994-02
• Application #: 3051109
• Study Section: Special Emphasis Panel (BI)
• Project Start: 1990-01-03
• Budget Start: 1990-01-03
• Budget End: 1991-01-02
• Support Year: 2
• Fiscal Year: 1990

Institution

• Name: Georgia Institute of Technology
• Type: Schools of Arts and Sciences
• DUNS #: 097394084
• City: Atlanta
• State: GA
• Country: United States
• Zip Code: 30332

Publications

Plaskon, R R; Kam, C M; Kerrigan, J E et al. (1993) Inhibition of porcine pancreatic elastase by 7-substituted 4-chloro-3-ethoxyisocoumarins: structural characteristics of modeled noncovalent complexes relate to the measured inhibition kinetics. Arch Biochem Biophys 300:588-97

Plaskon, R R; Kam, C M; Burgess, E M et al. (1992) Michaelis complexes of porcine pancreatic elastase with 7-[(alkylcarbamoyl)amino]-4-chloro-3-ethoxyisocoumarins: translational sampling of inhibitor position and kinetic measurements. Proteins 13:141-51