Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Postdoctoral Individual National Research Service Award (F32)
Project #
5F32HL010058-02
Application #
6043714
Study Section
Special Emphasis Panel (ZRG7-SSS-8 (43))
Project Start
1999-08-01
Project End
Budget Start
1999-08-01
Budget End
2000-07-31
Support Year
2
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Biomedical Engineering
Type
Schools of Engineering
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
DeLisser, Horace M; Helmke, Brian P; Cao, Gaoyuan et al. (2006) Loss of PECAM-1 function impairs alveolarization. J Biol Chem 281:8724-31
Davies, Peter F; Zilberberg, Jenny; Helmke, Brian P (2003) Spatial microstimuli in endothelial mechanosignaling. Circ Res 92:359-70
Davies, Peter F; Polacek, Denise C; Shi, Congzhu et al. (2002) The convergence of haemodynamics, genomics, and endothelial structure in studies of the focal origin of atherosclerosis. Biorheology 39:299-306
Helmke, Brian P; Davies, Peter F (2002) The cytoskeleton under external fluid mechanical forces: hemodynamic forces acting on the endothelium. Ann Biomed Eng 30:284-96
Davies, P F; Shi, C; Depaola, N et al. (2001) Hemodynamics and the focal origin of atherosclerosis: a spatial approach to endothelial structure, gene expression, and function. Ann N Y Acad Sci 947:7-16; discussion 16-7
Helmke, B P; Thakker, D B; Goldman, R D et al. (2001) Spatiotemporal analysis of flow-induced intermediate filament displacement in living endothelial cells. Biophys J 80:184-94
Zhang, J C; Kim, S; Helmke, B P et al. (2001) Analysis of SM22alpha-deficient mice reveals unanticipated insights into smooth muscle cell differentiation and function. Mol Cell Biol 21:1336-44
Helmke, B P; Goldman, R D; Davies, P F (2000) Rapid displacement of vimentin intermediate filaments in living endothelial cells exposed to flow. Circ Res 86:745-52
Levitan, I; Helmke, B P; Davies, P F (2000) A chamber to permit invasive manipulation of adherent cells in laminar flow with minimal disturbance of the flow field. Ann Biomed Eng 28:1184-93