Papapetropoulos, Andreas; Fulton, David; Lin, Michelle I et al. (2004) Vanadate is a potent activator of endothelial nitric-oxide synthase: evidence for the role of the serine/threonine kinase Akt and the 90-kDa heat shock protein. Mol Pharmacol 65:407-15
|
Fulton, David; Fontana, Jason; Sowa, Grzegorz et al. (2002) Localization of endothelial nitric-oxide synthase phosphorylated on serine 1179 and nitric oxide in Golgi and plasma membrane defines the existence of two pools of active enzyme. J Biol Chem 277:4277-84
|
Scotland, Ramona S; Morales-Ruiz, Manuel; Chen, Yan et al. (2002) Functional reconstitution of endothelial nitric oxide synthase reveals the importance of serine 1179 in endothelium-dependent vasomotion. Circ Res 90:904-10
|
Iwakiri, Yasuko; Tsai, Ming-Hung; McCabe, Timothy J et al. (2002) Phosphorylation of eNOS initiates excessive NO production in early phases of portal hypertension. Am J Physiol Heart Circ Physiol 282:H2084-90
|
Fontana, Jason; Fulton, David; Chen, Yan et al. (2002) Domain mapping studies reveal that the M domain of hsp90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO release. Circ Res 90:866-73
|
Fulton, D; Gratton, J P; Sessa, W C (2001) Post-translational control of endothelial nitric oxide synthase: why isn't calcium/calmodulin enough? J Pharmacol Exp Ther 299:818-24
|
Fairchild, T A; Fulton, D; Fontana, J T et al. (2001) Acidic hydrolysis as a mechanism for the cleavage of the Glu(298)-->Asp variant of human endothelial nitric-oxide synthase. J Biol Chem 276:26674-9
|
Gratton, J P; Morales-Ruiz, M; Kureishi, Y et al. (2001) Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells. J Biol Chem 276:30359-65
|
Rudic, R D; Bucci, M; Fulton, D et al. (2000) Temporal events underlying arterial remodeling after chronic flow reduction in mice: correlation of structural changes with a deficit in basal nitric oxide synthesis. Circ Res 86:1160-6
|