The use of antipsychotics has become increasingly prevalent in children and adolescents despite the paucity of evidence suggesting efficacy and safety. In a recent study evaluating antipsychotic use in the Texas Medicaid child and adolescent population, prevalence rates for total antipsychotic use increased 160% over a five-year period (1996 to 2000), with all of this increase attributable to atypical antipsychotics (+494%). The purpose of this study is to examine the recent trends (1994 to 2001) of antipsychotic use and effects on health care outcomes in children and adolescents. A total of five Medicaid states, geographically diverse, will be used to collect data. Prevalence is defined as the number of children and adolescents with at least one Medicaid prescription claim for an antipsychotic, regardless of subclass, per 1,000 enrollees. Total antipsychotic, typical antipsychotic and atypical antipsychotic prevalence rates will be determined. Age-specific and gender-specific prevalence rates will also be calculated. Documented diagnoses, duration of antipsychotic therapy, and concomitant psychotropic medication use will be assessed. Using Medicaid service utilization databases, the study will evaluate the documented use of antipsychotics and identify the primary sources of antipsychotic prescribing. Secondary analyses to be included in this study will assess total Medicaid expenditures, including drug costs and health care service utilization. These analyses will examine total antipsychotic, typical antipsychotic, and atypical antipsychotic Medicaid expenditures.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Postdoctoral Individual National Research Service Award (F32)
Project #
5F32MH068042-02
Application #
6751908
Study Section
Special Emphasis Panel (ZMH1-SRV-C (01))
Program Officer
Light, Enid
Project Start
2003-05-01
Project End
2004-08-31
Budget Start
2004-05-01
Budget End
2004-08-31
Support Year
2
Fiscal Year
2004
Total Cost
$18,805
Indirect Cost
Name
University of Texas Austin
Department
Administration
Type
Schools of Pharmacy
DUNS #
170230239
City
Austin
State
TX
Country
United States
Zip Code
78712
Patel, Nick C; Crismon, M Lynn; Hoagwood, Kimberly et al. (2006) Physician specialty associated with antipsychotic prescribing for youths in the Texas Medicaid program. Med Care 44:87-90