Neurological disease effects a large number of people in a broad range of age groups. A key step to understanding and curing these disorders is to determine the mechanisms controlling neural function. One of the most interesting questions in the field of neurobiology is how behavior is generated. The model organism C. elegans will be used to address this question as it has a simple and well characterized nervous system as well as other tools which will facilitate research. Specifically, a pathway will be defined that regulates male response to the hermaphrodite during mating. Genetic, molecular and ablation studies will be done to determine the neurons, neurotransmitters and signaling pathways mediating this behavior. Lessons learned from this study will both expand our knowledge of how behavior is generated and also of the general mechanisms controlling neural function.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Postdoctoral Individual National Research Service Award (F32)
Project #
5F32NS042497-03
Application #
6616175
Study Section
Special Emphasis Panel (ZRG1-MDCN-1 (01))
Program Officer
Babcock, Debra J
Project Start
2002-08-01
Project End
Budget Start
2003-08-01
Budget End
2004-07-31
Support Year
3
Fiscal Year
2003
Total Cost
$48,148
Indirect Cost
Name
California Institute of Technology
Department
Type
Schools of Arts and Sciences
DUNS #
009584210
City
Pasadena
State
CA
Country
United States
Zip Code
91125