Abstract

The parasitic protozoan Giardia lamblia, which is a major cause of waterborne enteric disease (giardiasis) throughout the world, exists in two morphologic forms, the active trophozoite and the dormant cyst. Trophozoites colonize the upper part of the human small intestine and cause disease, whereas the cyst form survives outside the host and is responsible for transmission. The main goal of this laboratory is to understand the cellular and molecular mechanisms of differentiation as well as the host-parasite interactions by Giardia.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Research Centers in Minority Institutions Award (G12)
Project #
5G12RR008124-05
Application #
5225706
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost

  Publications

Contreras, Lisett; Calderon, Ruben I; Varela-Ramirez, Armando et al. (2018) Induction of apoptosis via proteasome inhibition in leukemia/lymphoma cells by two potent piperidones. Cell Oncol (Dordr) 41:623-636
Portillo, Frank; Branch, William R; Conradie, Werner et al. (2018) Phylogeny and biogeography of the African burrowing snake subfamily Aparallactinae (Squamata: Lamprophiidae). Mol Phylogenet Evol 127:288-303
Cox, Marc B; Johnson, Jill L (2018) Evidence for Hsp90 Co-chaperones in Regulating Hsp90 Function and Promoting Client Protein Folding. Methods Mol Biol 1709:397-422
Del Rio, Michelle; Alvarez, Juan; Mayorga, Tania et al. (2017) A comparison of arsenic exposure in young children and home water arsenic in two rural West Texas communities. BMC Public Health 17:850
Sobin, Christina; Flores-Montoya, Mayra Gisel; Alvarez, Juan Manuel (2017) Early chronic low-level Pb exposure alters global exploratory behaviors but does not impair spatial and object memory retrieval in an object-in-place task in pre-adolescent C57BL/6J mice. Neurotoxicol Teratol 61:104-114
Aranda, Gissel P; Hinojos, Samantha J; Sabandal, Paul R et al. (2017) Behavioral Sensitization to the Disinhibition Effect of Ethanol Requires the Dopamine/Ecdysone Receptor in Drosophila. Front Syst Neurosci 11:56
Montoya, Alexa; Amaya, Clarissa N; Belmont, Andres et al. (2017) Use of non-selective ?-blockers is associated with decreased tumor proliferative indices in early stage breast cancer. Oncotarget 8:6446-6460
Iniguez, Eva; Schocker, Nathaniel S; Subramaniam, Krishanthi et al. (2017) An ?-Gal-containing neoglycoprotein-based vaccine partially protects against murine cutaneous leishmaniasis caused by Leishmania major. PLoS Negl Trop Dis 11:e0006039
Zimkus, Breda M; Lawson, Lucinda P; Barej, Michael F et al. (2017) Leapfrogging into new territory: How Mascarene ridged frogs diversified across Africa and Madagascar to maintain their ecological niche. Mol Phylogenet Evol 106:254-269
Dai, Liping; Peng, Xuan-Xian; Tan, Eng M et al. (2016) Tumor-associated antigen CAPER? and microvessel density in hepatocellular carcinoma. Oncotarget 7:16985-95

Showing the most recent 10 out of 327 publications