Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA067463-02
Application #
2111164
Study Section
Special Emphasis Panel (SRC (24))
Project Start
1995-04-01
Project End
1999-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Seo, Ji Hye; Fox, James G; Peek Jr, Richard M et al. (2011) N-methyl D-aspartate channels link ammonia and epithelial cell death mechanisms in Helicobacter pylori Infection. Gastroenterology 141:2064-75
Hagen, Susan J; Ohtani, Masa; Zhou, Jin-Rong et al. (2009) Inflammation and foveolar hyperplasia are reduced by supplemental dietary glutamine during Helicobacter pylori infection in mice. J Nutr 139:912-8
Hagen, Susan J; Yang, David X; Tashima, Kimihito et al. (2008) Epithelial cell expression of BCL-2 family proteins predicts mechanisms that regulate Helicobacter pylori-induced pathology in the mouse stomach. Lab Invest 88:1227-44
Shen, Z; Feng, Y; Fox, J G (2000) Identification of enterohepatic Helicobacter species by restriction fragment-length polymorphism analysis of the 16S rRNA gene. Helicobacter 5:121-8
Fox, J G; Dangler, C A; Taylor, N S et al. (1999) High-salt diet induces gastric epithelial hyperplasia and parietal cell loss, and enhances Helicobacter pylori colonization in C57BL/6 mice. Cancer Res 59:4823-8
Wang, T C; Dockray, G J (1999) Lessons from genetically engineered animal models. I. Physiological studies with gastrin in transgenic mice. Am J Physiol 277:G6-11
Lichtenberger, L M; Dial, E J; Ottlecz, A et al. (1999) Attenuation of hydrophobic phospholipid barrier is an early event in Helicobacter felis-induced gastritis in mice. Dig Dis Sci 44:108-15
Fox, J G (1998) Review article: Helicobacter species and in vivo models of gastrointestinal cancer. Aliment Pharmacol Ther 12 Suppl 1:37-60
Fox, J G; Dangler, C A; Whary, M T et al. (1997) Mice carrying a truncated Apc gene have diminished gastric epithelial proliferation, gastric inflammation, and humoral immunity in response to Helicobacter felis infection. Cancer Res 57:3972-8
Fox, J G; Dangler, C A; Sager, W et al. (1997) Helicobacter mustelae-associated gastric adenocarcinoma in ferrets (Mustela putorius furo). Vet Pathol 34:225-9

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